Characteristics and strength of evidence of COVID-19 studies registered on ClinicalTrials. gov

K Pundi, AC Perino, RA Harrington… - JAMA internal …, 2020 - jamanetwork.com
Characteristics and Strength of Evidence of COVID-19 Studies Registered on ClinicalTrials.gov |
Research, Methods, Statistics | JAMA Internal Medicine | JAMA Network [Skip to Navigation] Our …

Race and ethnicity reporting and representation in pediatric clinical trials

RCL Brewster, JR Steinberg, CJ Magnani… - …, 2023 - publications.aap.org
Video Abstract BACKGROUND AND OBJECTIVES Representative enrollment of racial and
ethnic minoritized populations in biomedical research ensures the generalizability of results …

Early discontinuation, results reporting, and publication of pediatric clinical trials

R Brewster, M Wong, CJ Magnani, H Gunningham… - …, 2022 - publications.aap.org
METHODS Cross-sectional analysis of clinical trials enrolling participants< 18 years old
registered at ClinicalTrials. gov from October 2007 to March 2020. Multivariable logistic …

Analysis of rates of completion, delays, and participant recruitment in randomized clinical trials in surgery

C Shadbolt, E Naufal, S Bunzli, V Price… - JAMA Network …, 2023 - jamanetwork.com
Importance Discontinuation and nonpublication are established sources of avoidable waste
among surgical trials, but rates of delayed completion and recruiting shortfalls remain …

The international clinical trials registry platform (ICTRP): data integrity and the trends in clinical trials, diseases, and drugs

ED Namiot, D Smirnovová, AV Sokolov… - Frontiers in …, 2023 - frontiersin.org
Introduction: Clinical trials are the gold standard for testing new therapies. Databases like
ClinicalTrials. gov provide access to trial information, mainly covering the US and Europe. In …

The obstetrical research landscape: a cross-sectional analysis of clinical trials from 2007-2020

JR Steinberg, BT Weeks, GA Reyes… - American Journal of …, 2021 - Elsevier
Background Obstetrical complications affect more than a third of women globally, but are
underrepresented in clinical research. Little is known about the comprehensive obstetrical …

Clinical trial outcomes in urology: assessing early discontinuation, results reporting and publication in ClinicalTrials. Gov registrations 2007–2019

CJ Magnani, JR Steinberg, CI Harmange… - The Journal of …, 2021 - auajournals.org
Purpose: Clinical trials require significant resources, but benefits are only realized after trial
completion and dissemination of results. We comprehensively assessed early …

A technical review of three clinical trials register resources indicates where improvements to the search interfaces are needed

C Cooper, R Court, E Kotas… - Research Synthesis …, 2021 - Wiley Online Library
Clinical trials registers form an important part of the search for studies in systematic reviews
of intervention effectiveness but the search interfaces and functionality of registers can be …

Characteristics and research waste among randomized clinical trials in gastric cancer

J Lu, B Xu, L Shen, D Wu, Z Xue, HL Zheng… - JAMA network …, 2021 - jamanetwork.com
Importance The results of numerous large randomized clinical trials (RCTs) have changed
clinical practice in gastric cancer (GC). However, research waste (ie, unpublished data …

The landscape of acute pancreatitis trials registered in ClinicalTrials. gov: a cross-sectional study

J Jiang, S Huang, H Xia, K Zou, X Zeng, H Zhang… - Pancreas, 2022 - journals.lww.com
Objectives Clinical studies are important in informing evidence-based practice for patients
with acute pancreatitis (AP). To determine whether registered studies adequately meet this …