Functional connectomics spanning multiple areas of mouse visual cortex

MICrONS Consortium, JA Bae, M Baptiste, CA Bishop… - BioRxiv, 2021 - biorxiv.org
To understand the brain we must relate neurons' functional responses to the circuit
architecture that shapes them. Here, we present a large functional connectomics dataset …

Cell-type-specific inhibitory circuitry from a connectomic census of mouse visual cortex

CM Schneider-Mizell, AL Bodor, D Brittain… - …, 2024 - pmc.ncbi.nlm.nih.gov
Mammalian cortex features a vast diversity of neuronal cell types, each with characteristic
anatomical, molecular and functional properties. Synaptic connectivity powerfully shapes …

Functional connectomics reveals general wiring rule in mouse visual cortex

Z Ding, PG Fahey, S Papadopoulos, EY Wang… - …, 2024 - pmc.ncbi.nlm.nih.gov
Understanding the relationship between circuit connectivity and function is crucial for
uncovering how the brain implements computation. In the mouse primary visual cortex (V1) …

Learning meaningful representation of single-neuron morphology via large-scale pre-training

Y Fan, Y Li, Y Zhong, L Hong, L Li, Y Li - Bioinformatics, 2024 - academic.oup.com
Single-neuron morphology, the study of the structure, form, and shape of a group of
specialized cells in the nervous system, is of vital importance to define the type of neurons …

Quantitative census of local somatic features in mouse visual cortex

L Elabbady, S Seshamani, S Mu, G Mahalingam… - bioRxiv, 2022 - biorxiv.org
Mammalian neocortex contains a highly diverse set of cell types. These types have been
mapped systematically using a variety of molecular, electrophysiological and morphological …

NEURD: automated proofreading and feature extraction for connectomics

B Celii - 2024 - search.proquest.com
We are now in the era of millimeter-scale electron microscopy (EM) volumes collected at
nanometer resolution. Dense reconstruction of cellular compartments in these EM volumes …

Semantic segmentation of pyramidal neuron skeletons using geometric deep learning.

L Li, J Qi, Y Geng, J Wu - Journal of Innovative Optical …, 2023 - search.ebscohost.com
Neurons can be abstractly represented as skeletons due to the filament nature of neurites.
With the rapid development of imaging and image analysis techniques, an increasing …

The Synaptic Architecture of Layer 5 Thick Tufted Excitatory Neurons in the Visual Cortex of Mice

AL Bodor, CM Schneider-Mizell, C Zhang, L Elabbady… - bioRxiv, 2023 - biorxiv.org
The neocortex is one of the most critical structures that makes us human, and it is involved in
a variety of cognitive functions from perception to sensory integration and motor control …