[HTML][HTML] The prevention of restenosis in vivo with a VEGF gene and paclitaxel co-eluting stent

J Yang, Y Zeng, C Zhang, YX Chen, Z Yang, Y Li… - Biomaterials, 2013 - Elsevier
Long-term clinical studies of drug-eluting stents (DES) have reported high incidence of late
thrombosis. Given the growing concern over the clinical application of this technology, we …

Inflammatory growth factors and in-stent restenosis: effect of cytokines and growth factors

M Maleknia, N Ansari, H Haybar, M Maniati… - SN Comprehensive …, 2020 - Springer
Following stent implantation and vascular injury, restenosis is one of the prominent clinical
problems due to the synergism effects of inflammatory cytokines and growth factors …

Optimization of drug delivery by drug-eluting stents

F Bozsak, D Gonzalez-Rodriguez, Z Sternberger… - PloS one, 2015 - journals.plos.org
Drug-eluting stents (DES), which release anti-proliferative drugs into the arterial wall in a
controlled manner, have drastically reduced the rate of in-stent restenosis and …

Factors influencing 1st and 2nd generation drug-eluting stent performance: Understanding the basic pharmaceutical drug-in-polymer formulation factors contributing …

I Srdanovic - Journal of Pharmacy & Pharmaceutical …, 2021 - journals.library.ualberta.ca
Drug-eluting stents (DES) have a major role in treating cardiovascular disease. The
evolution of bare metal stents into 1 st generation durable-polymer DES (DP-DES) reduced …

Reduction in migratory phenotype in a metastasized breast cancer cell line via downregulation of S100A4 and GRM3

A Chen, L Wang, BY Li, J Sherman, JE Ryu… - Scientific reports, 2017 - nature.com
To investigate phenotypic and genotypic alterations before and after bone metastasis, we
conducted genome-wide mRNA profiling and DNA exon sequencing of two cell lines (TMD …

The zebrafish ventricle: A hub of cardiac endothelial cells for in vitro cell behavior studies

C Patra, Z Kontarakis, H Kaur, A Rayrikar… - Scientific reports, 2017 - nature.com
Despite our increasing understanding of zebrafish heart development and regeneration,
there is limited information about the distribution of endothelial cells (ECs) in the adult …

Effects of elemene on inhibiting proliferation of vascular smooth muscle cells and promoting reendothelialization at the stent implantation site

W Sun, Y Huang, T Yin, J Wang, R Du, J Qiu… - Biomaterials …, 2017 - pubs.rsc.org
Anticancer drugs are commonly used as inhibitors of vascular smooth muscle cell (VSMC)
proliferation in clinical treatments. This study aims to investigate how elemene affects the …

Exploration of the Pharmacophore for Cytoskeletal Targeting Ruthenium Polypyridyl Complexes

MM Reardon, M Guerrero, N Alatrash… - …, 2023 - Wiley Online Library
Ruthenium (II) trisdiimine complexes of the formula,[Ru (dip) n (L− L) 3‐n] 2+, where n= 0‐3;
dip= 4, 7‐diphenyl‐1, 10‐phenanthroline; L–L= 2, 2'‐bipyridine (bpy) or 1, 10 …

The interleukin-1β modulator gevokizumab reduces neointimal proliferation and improves reendothelialization in a rat carotid denudation model

F Roubille, D Busseuil, Y Shi, W Nachar… - Atherosclerosis, 2014 - Elsevier
Objective Excessive neointima formation often occurs after arterial injury. Interleukin-1β (IL-
1β) is a potent pleiotropic cytokine that has been shown to regulate neointimal proliferation …

Inhibition effect of tacrolimus and platelet-derived growth factor-BB on restenosis after vascular intimal injury

X Ma, C Jiang, Y Li, L Feng, J Liu, J Wang - Biomedicine & …, 2017 - Elsevier
Excessive proliferation and migration of vascular smooth muscle cells (VSMCs) and delayed
proliferation and migration of endothelial cells (ECs) were the main cause of restenosis after …