There is highly credible evidence that melatonin mitigates cancer at the initiation,
progression and metastasis phases. In many cases, the molecular mechanisms …

Diabetic wounds are characterized by incomplete healing and delayed healing, resulting in
a considerable global health care burden. Exosomes are lipid bilayer structures secreted by …

Spinal cord injury (SCI) is a devastating condition that results in sensory and motor
dysfunctions below the injury site. Currently, there is no effective treatment. Extracellular …

During the last two decades, melatonin has been found to have pleiotropic effects via
different mechanisms on its target cells. Data are abundant for some aspects of the signaling …

Dendritic cells (DCs) are innate immune cells which engulf, process and present antigens to
the naïve T-lymphocyte cells. However, little is known about the effect of melatonin on the …

The therapeutic outcomes of exosome-based therapies have greatly exceeded initial
expectations in many clinically intractable diseases due to the safety, low toxicity, and …

Telocytes are a special type of interstitial cells characterized by distinctive cellular
extensions with alternating thin segments (podomers) and dilations (podoms). Telocytes …

In the Merino ram, it is unclear whether cryopreserved sperm function and fertility is
compromised when collected during the non-breeding season, when Merino ewes are …

Telocytes (TCs) are a distinct stromal cell type described in many organs. The present study
investigated the existence of TCs within the efferent ductules in camel and the changes that …

This review presents recent findings on the effect of melatonin on ram spermatozoa. This
hormone regulates seasonal reproduction in the ovine species through the hypothalamic …