The Ccr4‐Not complex is a key regulator of eukaryotic gene expression
MA Collart - Wiley Interdisciplinary Reviews: RNA, 2016 - Wiley Online Library
The Ccr4‐Not complex is a multisubunit complex present in all eukaryotes that contributes to
regulate gene expression at all steps, from production of messenger RNAs (mRNAs) in the …
regulate gene expression at all steps, from production of messenger RNAs (mRNAs) in the …
Multifunctional roles of the mammalian CCR4–NOT complex in physiological phenomena
YT Shirai, T Suzuki, M Morita, A Takahashi… - Frontiers in …, 2014 - frontiersin.org
The carbon catabolite repression 4 (CCR4)–negative on TATA-less (NOT) complex serves
as one of the major deadenylases of eukaryotes. Although it was originally identified and …
as one of the major deadenylases of eukaryotes. Although it was originally identified and …
RNA helicase DDX6 and scaffold protein GW182 in P-bodies promote biogenesis of stress granules
V Majerciak, T Zhou, MJ Kruhlak… - Nucleic Acids …, 2023 - academic.oup.com
Two prominent cytoplasmic RNA granules, ubiquitous RNA-processing bodies (PB) and
inducible stress granules (SG), regulate mRNA translation and are intimately related. In this …
inducible stress granules (SG), regulate mRNA translation and are intimately related. In this …
Personalized immunotherapy against several neuronal and brain tumors
S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …
A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape
Interferon-stimulated genes (ISGs) form the backbone of the innate immune system and are
important for limiting intra-and intercellular viral replication and spread. We conducted a …
important for limiting intra-and intercellular viral replication and spread. We conducted a …
Immunotherapy against several tumors, such as lung cancer, including NSCLC
T Weinschenk, S Walter, J Fritsche, S Colette… - US Patent …, 2018 - Google Patents
A method of treating a patient who has non-small cell lung carcinoma (NSCLC), lung cancer,
gastric cancer, and/or glioblastoma includes administering to said patient a composition …
gastric cancer, and/or glioblastoma includes administering to said patient a composition …
Immunotherapy against several tumors, such as lung cancer, including nsclc
T Weinschenk, S Walter, J Fritsche… - US Patent App. 14 …, 2016 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
52460698&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
52460698&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
Cytidine-containing tails robustly enhance and prolong protein production of synthetic mRNA in cell and in vivo
Synthetic mRNAs are rising rapidly as alternative therapeutic agents for delivery of proteins.
However, the practical use of synthetic mRNAs has been restricted by their low cellular …
However, the practical use of synthetic mRNAs has been restricted by their low cellular …
Novel immunotherapy against several tumors, such as lung cancer, including nsclc
T Weinschenk, S Walter, J Fritsche, S Colette, H Singh - 2015 - Google Patents
The present invention relates to peptides, nucleic acids and cells for use in
immunotherapeutic methods. In particular, the present invention relates to the …
immunotherapeutic methods. In particular, the present invention relates to the …
Structure and assembly of the NOT module of the human CCR4–NOT complex
The CCR4–NOT deadenylase complex is a master regulator of translation and mRNA
stability. Its NOT module orchestrates recruitment of the catalytic subunits to target mRNAs …
stability. Its NOT module orchestrates recruitment of the catalytic subunits to target mRNAs …