Invited review: the preterm pig as a model in pediatric gastroenterology

PT Sangild, T Thymann, M Schmidt… - Journal of animal …, 2013 - academic.oup.com
At birth, the newborn mammal undergoes a transition from a sterile uterine environment with
a constant nutrient supply, to a microbe-rich environment with intermittent oral intake of …

[HTML][HTML] Nutritional factors influencing intestinal health of the neonate

SK Jacobi, J Odle - Advances in nutrition, 2012 - Elsevier
Dietary nutrients are essential for gastrointestinal (GI) growth and function, and nutritional
support of GI growth and development is a significant component of infant care. For healthy …

The suckling piglet as an agrimedical model for the study of pediatric nutrition and metabolism

J Odle, X Lin, SK Jacobi, SW Kim… - Annu. Rev. Anim …, 2014 - annualreviews.org
The neonatal pig ranks among the most prominent research models for the study of pediatric
nutrition and metabolism. Its precocial development at birth affords ready adaptation to …

Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs

AK Jain, B Stoll, DG Burrin, JJ Holst… - American Journal of …, 2012 - journals.physiology.org
Total parenteral nutrition (TPN) is essential for patients with impaired gut function but leads
to parenteral nutrition-associated liver disease (PNALD). TPN disrupts the normal …

Nutritional support strategies for the preterm infant in the neonatal intensive care unit

WW Hay - Pediatric gastroenterology, hepatology & nutrition, 2018 - synapse.koreamed.org
The goal of nutrition of the preterm infant is to “provide nutrients to approximate the rate of
growth and composition of weight gain for a normal fetus of the same postmenstrual age and …

Translational advances in pediatric nutrition and gastroenterology: new insights from pig models

D Burrin, PT Sangild, B Stoll, T Thymann… - Annual review of …, 2020 - annualreviews.org
Pigs are increasingly important animals for modeling human pediatric nutrition and
gastroenterology and complementing mechanistic studies in rodents. The comparative …

Optimizing nutrition of the preterm infant

W WHay Jr - Chinese Journal of Contemporary Pediatrics, 2017 - pmc.ncbi.nlm.nih.gov
Objective The goal of nutrition of the preterm infant is to meet the growth rate of the healthy
fetus of the same gestational age and to produce the same body composition of the healthy …

Parenteral nutrition-associated liver injury: clinical relevance and mechanistic insights

M Mihajlovic, Z Rosseel, E De Waele… - Toxicological …, 2024 - academic.oup.com
Intestinal failure-associated liver disease (IFALD) is a relatively common complication in
individuals receiving parenteral nutrition (PN). IFALD can be manifested as different types of …

New generation lipid emulsions prevent PNALD in chronic parenterally fed preterm pigs

H Vlaardingerbroek, K Ng, B Stoll, N Benight… - Journal of lipid …, 2014 - ASBMB
Total parenteral nutrition (TPN) is associated with the development of parenteral nutrition-
associated liver disease (PNALD) in infants. Fish oil-based lipid emulsions can reverse …

[HTML][HTML] Impact of new-generation lipid emulsions on cellular mechanisms of parenteral nutrition–associated liver disease

DG Burrin, K Ng, B Stoll, MS De Pipaón - Advances in nutrition, 2014 - Elsevier
Parenteral nutrition (PN) is a life-saving nutritional support for a large population of
hospitalized infants, and lipids make a substantial contribution to their energy and essential …