Spiers Memorial Lecture: Mechanochemistry, tribochemistry, mechanical alloying–retrospect, achievements and challenges

E Boldyreva - Faraday discussions, 2023 - pubs.rsc.org
Spiers Memorial Lecture: Mechanochemistry, tribochemistry, mechanical alloying –
retrospect, achievements and challenges - Faraday Discussions (RSC Publishing) DOI:10.1039/D2FD00149G …

Characterization of pharmaceutical tablets by X-ray tomography

J Vijayakumar, NM Goudarzi, G Eeckhaut… - Pharmaceuticals, 2023 - mdpi.com
Solid dosage forms such as tablets are extensively used in drug administration for their
simplicity and large-scale manufacturing capabilities. High-resolution X-ray tomography is …

Moisture behavior of pharmaceutical powder during the tableting process

K Koumbogle, R Gosselin, F Gitzhofer, N Abatzoglou - Pharmaceutics, 2023 - mdpi.com
The moisture content of pharmaceutical powder is a key parameter contributing to tablet
sticking during the tableting process. This study investigates powder moisture behavior …

Effect of temperature increase during the tableting of pharmaceutical materials

M Cespi, G Bonacucina, L Casettari, S Ronchi… - International journal of …, 2013 - Elsevier
Scale-up of tableting process is particularly difficult due to specific concerns related
exclusively to the process itself and that cannot be determined on a smaller scale, which are …

Numerical evaluation of the capping tendency of microcrystalline cellulose tablets during a diametrical compression test

R Furukawa, Y Chen, A Horiguchi, K Takagaki… - International journal of …, 2015 - Elsevier
Capping is one of the major problems that occur during the tabletting process in the
pharmaceutical industry. This study provided an effective method for evaluating the capping …

Evolution of the microstructure during the process of consolidation and bonding in soft granular solids

B Yohannes, M Gonzalez, A Abebe, O Sprockel… - International journal of …, 2016 - Elsevier
The evolution of microstructure during powder compaction process was investigated using a
discrete particle modeling, which accounts for particle size distribution and material …

Finite element analysis and modeling in pharmaceutical tableting

I Partheniadis, V Terzi, I Nikolakakis - Pharmaceutics, 2022 - mdpi.com
Finite element analysis (FEA) is a computational method providing numerical solutions and
mathematical modeling of complex physical phenomena that evolve during compression …

Discrete particle modeling and micromechanical characterization of bilayer tablet compaction

B Yohannes, M Gonzalez, A Abebe, O Sprockel… - International journal of …, 2017 - Elsevier
A mechanistic particle scale model is proposed for bilayer tablet compaction. Making bilayer
tablets involves the application of first layer compaction pressure on the first layer powder …

Evaluation of In-Die Compression Data for a Deeper Understanding of Altered Excipient Properties upon Temperature Rise

HD Grumann, S Klinken, P Kleinebudde - AAPS PharmSciTech, 2023 - Springer
The thermodynamic analysis of tablet formation includes the thermal and mechanical
analysis during compression. The aim of this study was to evaluate alterations of force …

Spatial and temporal visualization of polymorphic transformations in pharmaceutical tablets

J Gasol‐Cardona, MR Ward, O Gutowski… - Angewandte …, 2025 - Wiley Online Library
Abstract X‐ray Diffraction Computed Tomography (XRD‐CT) represents a cutting‐edge
method for non‐destructive material analysis, offering the unique capability of providing …