The contribution of the exposome to the burden of cardiovascular disease

T Münzel, M Sørensen, O Hahad… - Nature Reviews …, 2023 - nature.com
Large epidemiological and health impact assessment studies at the global scale, such as
the Global Burden of Disease project, indicate that chronic non-communicable diseases …

Spotlight on microRNAs in allergy and asthma

J Weidner, S Bartel, A Kılıç, UM Zissler, H Renz… - Allergy, 2021 - Wiley Online Library
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …

Regulatory mechanisms of microRNA expression

LF Gulyaeva, NE Kushlinskiy - Journal of translational medicine, 2016 - Springer
MicroRNAs (miRs, miRNAs) are small molecules of 18–22 nucleotides that serve as
important regulators of gene expression at the post-transcriptional level. One of the …

Endocrine disruptors acting on estrogen and androgen pathways cause reproductive disorders through multiple mechanisms: a review

S Amir, STA Shah, C Mamoulakis, AO Docea… - International Journal of …, 2021 - mdpi.com
Increasing contamination of the environment by toxic compounds such as endocrine
disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both …

Re-evaluation of the WHO (2010) formaldehyde indoor air quality guideline for cancer risk assessment

GD Nielsen, ST Larsen, P Wolkoff - Archives of toxicology, 2017 - Springer
Abstract In 2010, the World Health Organization (WHO) established an indoor air quality
guideline for short-and long-term exposures to formaldehyde (FA) of 0.1 mg/m 3 (0.08 ppm) …

miRNA: a diagnostic and therapeutic tool for pancreatic cancer

MI Qadir, A Faheem - Critical Reviews™ in Eukaryotic Gene …, 2017 - dl.begellhouse.com
Pancreatic ductal adenocarcinoma (PDAC) is fatal disease and one of the major causes of
death among cancer patients. Diagnosis of PDAC during the early stages of cancer using …

Fine particulate air pollution and the expression of microRNAs and circulating cytokines relevant to inflammation, coagulation, and vasoconstriction

R Chen, H Li, J Cai, C Wang, Z Lin, C Liu… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: MicroRNAs (miRNAs) are a key factor in epigenetic regulation of gene
expression, but miRNA responses to fine particulate matter (PM 2.5) air pollution and their …

Ageing: from inflammation to cancer

GC Leonardi, G Accardi, R Monastero, F Nicoletti… - Immunity & …, 2018 - Springer
Ageing is the major risk factor for cancer development. Hallmark of the ageing process is
represented by inflammaging, which is a chronic and systemic low-grade inflammatory …

Arsenic-induced changes in miRNA expression in cancer and other diseases

APF Cardoso, KT Udoh, JC States - Toxicology and applied pharmacology, 2020 - Elsevier
Abstract miRNAs (miRNA) are essential players regulating gene expression affecting
cellular processes contributing to disease development. Dysregulated miRNA expression …

Nutrimiromics: role of microRNAs and nutrition in modulating inflammation and chronic diseases

BJ Quintanilha, BZ Reis, GBS Duarte, SMF Cozzolino… - Nutrients, 2017 - mdpi.com
Nutrimiromics studies the influence of the diet on the modification of gene expression due to
epigenetic processes related to microRNAs (miRNAs), which may affect the risk for the …