Neuromyelitis optica spectrum disorders (NMOSD) are mostly relapsing inflammatory
disorders of the central nervous system (CNS). Optic neuritis (ON) is the first NMOSD-related …

Introduction Immunotherapies for multiple sclerosis (MS) significantly decrease the risk of
new relapses. However, the chronic compartmentalized inflammation and …

Background and Objectives Siponimod is an oral, selective sphingosine-1-phosphate
receptor-1/5 modulator approved for treatment of multiple sclerosis. Methods Mouse MRI …

ABSTRACT Introduction: Multiple Sclerosis (MS) is the most common chronic autoimmune
neuroinflammatory condition in young adults. It is often accompanied by optic neuritis (ON) …

Objectives To measure early structural damage caused by autoimmune inflammatory optic
neuritis (ON) by optical coherence tomography (OCT) in a population‐based cohort …

Optic neuritis remains a clinical diagnosis; increasingly optical coherence tomography is a
key ancillary investigation. Patients with 'typical'optic neuritis, commonly a first presentation …

Optical coherence tomography (OCT) has emerged as a fast, non-invasive, inexpensive,
high-resolution imaging technique in multiple sclerosis (MS). Retinal layer quantification by …

Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are
autoimmune central nervous system conditions with increasing incidence and prevalence …

Background Retinal optical coherence tomography (OCT) is a clinical and research tool in
multiple sclerosis, where it has shown significant retinal nerve fiber (RNFL) and ganglion …

Background and Objective Erythropoietin (EPO) is a candidate neuroprotective drug. We
assessed its long-term safety and efficacy as an adjunct to methylprednisolone in patients …