Dendritic cells (DCs) can be viewed as translators between innate and adaptive immunity.
They integrate signals derived from tissue infection or damage and present processed …

Asthma is a chronic disease of the airways, which affects more than 350 million people
worldwide. It is the most common chronic disease in children, affecting at least 30 million …

Dendritic cells (DCs) of the cDC2 lineage initiate allergic immunity and in the dermis are
marked by their expression of CD301b. CD301b+ dermal DCs respond to allergens …

Microbial infections are recognized by the innate immune system both to elicit immediate
defense and to generate long-lasting adaptive immunity. To detect and respond to vastly …

The skin provides both a physical barrier and an immunologic barrier to external threats. The
protective machinery of the skin has evolved to provide situation-specific responses to …

Neutrophils are predominant immune cells that protect the human body against infections by
deploying sophisticated antimicrobial strategies including phagocytosis of bacteria and …

Asthma is a common disease that affects 300 million people worldwide. Given the large
number of eosinophils in the airways of people with mild asthma, and verified by data from …

It is estimated that more than 339 million people worldwide suffer from asthma. The leading
cause of asthma development is the breakdown of immune tolerance to inhaled allergens …

Dendritic cells (DCs) play critical roles in activating innate immune cells and initiating
adaptive immune responses. The functions of DCs were originally obscured by their overlap …

Naive CD4+ T cell differentiation into distinct subsets of T helper (Th) cells is a pivotal
process in the initiation of the adaptive immune response. Allergens predominantly stimulate …