Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis
N Ahmad, SD Ahuja, OW Akkerman, JWC Alffenaar… - The Lancet, 2018 - thelancet.com
Background Treatment outcomes for multidrug-resistant tuberculosis remain poor. We aimed
to estimate the association of treatment success and death with the use of individual drugs …
to estimate the association of treatment success and death with the use of individual drugs …
The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …
tuberculosis remains out of control in several parts of the world including Africa and Asia …
Treatment of drug-resistant tuberculosis. An official ATS/CDC/ERS/IDSA clinical practice guideline
Background: The American Thoracic Society, US Centers for Disease Control and
Prevention, European Respiratory Society, and Infectious Diseases Society of America …
Prevention, European Respiratory Society, and Infectious Diseases Society of America …
Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis
Background Treatment of multidrug-resistant tuberculosis requires long-term therapy with a
combination of multiple second-line drugs. These drugs are associated with numerous …
combination of multiple second-line drugs. These drugs are associated with numerous …
Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care
N Dookie, S Rambaran, N Padayatchi… - Journal of …, 2018 - academic.oup.com
Abstract Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and
control programmes worldwide. Advances in sequencing technology have significantly …
control programmes worldwide. Advances in sequencing technology have significantly …
Effect of bedaquiline on mortality in South African patients with drug-resistant tuberculosis: a retrospective cohort study
Background Addition of bedaquiline to treatment for multidrug-resistant tuberculosis was
associated with an increased risk of death in a phase 2b clinical trial, resulting in caution …
associated with an increased risk of death in a phase 2b clinical trial, resulting in caution …
Resistencia bacteriana a los antibióticos: una crisis global
JI Alós - Enfermedades infecciosas y microbiología clínica, 2015 - Elsevier
La introducción de los antibióticos en la práctica clínica supuso una de las intervenciones
más importantes para el control de las enfermedades infecciosas. Los antibióticos han …
más importantes para el control de las enfermedades infecciosas. Los antibióticos han …
Bedaquiline in the treatment of multidrug-and extensively drug-resistant tuberculosis
Bedaquiline, a diarylquinoline, improved cure rates when added to a multidrug-resistant
tuberculosis (MDR-TB) treatment regimen in a previous placebo-controlled, phase 2 trial …
tuberculosis (MDR-TB) treatment regimen in a previous placebo-controlled, phase 2 trial …
Drug‐resistant tuberculosis: an update on disease burden, diagnosis and treatment
The emergence of antimicrobial resistance against Mycobacterium tuberculosis, the leading
cause of mortality due to a single microbial pathogen worldwide, represents a growing threat …
cause of mortality due to a single microbial pathogen worldwide, represents a growing threat …
Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance
Multidrug-resistant tuberculosis (MDR-TB), caused by drug-resistant strains of
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …