Gender medicine: effects of sex and gender on cardiovascular disease manifestation and outcomes

V Regitz-Zagrosek, C Gebhard - Nature Reviews Cardiology, 2023 - nature.com
Despite a growing body of evidence, the distinct contributions of biological sex and the
sociocultural dimension of gender to the manifestations and outcomes of ischaemic heart …

Heart–brain interactions in cardiac and brain diseases: why sex matters

A Rossi, N Mikail, S Bengs, A Haider… - European heart …, 2022 - academic.oup.com
Cardiovascular disease and brain disorders, such as depression and cognitive dysfunction,
are highly prevalent conditions and are among the leading causes limiting patient's quality …

Sexual dimorphism in cardiovascular biomarkers: clinical and research implications

ES Lau, A Binek, SJ Parker, SH Shah… - Circulation …, 2022 - Am Heart Assoc
Sex-based differences in cardiovascular disease presentation, diagnosis, and response to
therapies are well established, but mechanistic understanding and translation to clinical …

[HTML][HTML] Myocardial infarction signs and symptoms: females vs. males

KJ Schulte, HN Mayrovitz - Cureus, 2023 - ncbi.nlm.nih.gov
Cardiovascular disease is the number one killer of females in the United States today, and
myocardial infarction (MI) plays a role in many of these deaths. Females also present with …

Epigenetic role of N6-methyladenosine (m6A) RNA methylation in the cardiovascular system

K Zhao, C Yang, P Li, W Sun, X Kong - Journal of Zhejiang University …, 2020 - Springer
As the most prevalent and abundant transcriptional modification in the eukaryotic genome,
the continuous and dynamic regulation of N 6-methyladenosine (m 6 A) has been shown to …

Sex differences in the inflammatory response: pharmacological opportunities for therapeutics for coronary artery disease

A Shabbir, KS Rathod, RS Khambata… - Annual review of …, 2021 - annualreviews.org
Coordinated molecular responses are key to effective initiation and resolution of both acute
and chronic inflammation. Vascular inflammation plays an important role in initiating and …

Susceptibility of Women to Cardiovascular Disease and the Prevention Potential of Mind–Body Intervention by Changes in Neural Circuits and Cardiovascular …

HJ Yang, E Koh, Y Kang - Biomolecules, 2021 - mdpi.com
Women have been reported to be more vulnerable to the development, prognosis and
mortality of cardiovascular diseases, yet the understanding of the underlying mechanisms …

Myocardial 18F-FDG Uptake Pattern for Cardiovascular Risk Stratification in Patients Undergoing Oncologic PET/CT

A Haider, S Bengs, K Schade, WJ Wijnen… - Journal of clinical …, 2020 - mdpi.com
Objective: Positron emission tomography/computed tomography with 18F-fluorodeoxy-
glucose (18F-FDG-PET/CT) has become the standard staging modality in various tumor …

The influence of inflammation on cardiovascular disease in women

S Kottilil, P Mathur - Frontiers in global women's health, 2022 - frontiersin.org
The onset of cardiovascular disease in women is almost a decade later than men, partly due
to the protective effect of estrogen prior to menopause. Recently, it was noted that while …

Sex-dependent association between inflammation, neural stress responses, and impaired myocardial function

M Fiechter, A Haider, S Bengs, M Marędziak… - European journal of …, 2020 - Springer
Purpose Evidence to date has failed to reveal unique female determinants of cardiovascular
disease. However, a strong association was recently observed between increased …