Transient receptor potential channels as drug targets: from the science of basic research to the art of medicine
The large Trp gene family encodes transient receptor potential (TRP) proteins that form
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
novel cation-selective ion channels. In mammals, 28 Trp channel genes have been …
Plant volatiles: production, function and pharmacology
Covering: 1989 to February 2011 Plant volatiles typically occur as a complex mixture of low-
molecular weight lipophilic compounds derived from different biosynthetic pathways, and …
molecular weight lipophilic compounds derived from different biosynthetic pathways, and …
TRPM8 is the principal mediator of menthol-induced analgesia of acute and inflammatory pain
B Liu, L Fan, S Balakrishna, A Sui, JB Morris, SE Jordt - Pain®, 2013 - Elsevier
Menthol, the cooling natural product of peppermint, is widely used in medicinal preparations
for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful …
for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful …
Medicinal plants utilized in the management of epilepsy in Ethiopia: ethnobotany, pharmacology and phytochemistry
YS Birhan - Chinese Medicine, 2022 - Springer
Epilepsy is a common central nervous system (CNS) disorder that affects 50 million people
worldwide. Patients with status epilepticus (SE) suffer from devastating comorbidities and a …
worldwide. Patients with status epilepticus (SE) suffer from devastating comorbidities and a …
[HTML][HTML] Essential oils: Chemical constituents, potential neuropharmacological effects and aromatherapy-A review
J Liang, Y Zhang, P Chi, H Liu, Z Jing, H Cao… - Pharmacological …, 2023 - Elsevier
Abstract Background Essential oils (EOs) are a plant-derived volatile mixture. Due to their
extensive biological activity, EOs have been utilized as ancient remedies to treat a variety of …
extensive biological activity, EOs have been utilized as ancient remedies to treat a variety of …
Volatile Terpenes and Brain Function: Investigation of the Cognitive and Mood Effects of Mentha × Piperita L. Essential Oil with In Vitro Properties Relevant to Central …
Background: Extracts of several members of the monoterpene-rich Lamiaceae sub-family
Nepetoideae, including those from the Salvia (sage), Melissa (Lemon balm) and …
Nepetoideae, including those from the Salvia (sage), Melissa (Lemon balm) and …
Pharmacologically targeting transient receptor potential channels for seizures and epilepsy: emerging preclinical evidence of druggability
As one of the most prevalent and disabling brain disorders, epilepsy is characterized by
spontaneous seizures that result from aberrant, excessive hyperactivity of a group of highly …
spontaneous seizures that result from aberrant, excessive hyperactivity of a group of highly …
Cellular and molecular targets of menthol actions
M Oz, EG El Nebrisi, KHS Yang, FC Howarth… - Frontiers in …, 2017 - frontiersin.org
Menthol belongs to monoterpene class of a structurally diverse group of phytochemicals
found in plant-derived essential oils. Menthol is widely used in pharmaceuticals …
found in plant-derived essential oils. Menthol is widely used in pharmaceuticals …
Menthol-pharmacology of an important naturally medicinal “cool”
JA Farco, O Grundmann - Mini reviews in medicinal chemistry, 2013 - ingentaconnect.com
Menthol, a natural product of the peppermint plant Mentha x piperita (Lamiaceae), is a
monoterpene which is widely used as a natural product in cosmetics, a flavoring agent, and …
monoterpene which is widely used as a natural product in cosmetics, a flavoring agent, and …
The distinctive role of menthol in pain and analgesia: Mechanisms, practices, and advances
Menthol is an important flavoring additive that triggers a cooling sensation. Under
physiological condition, low to moderate concentrations of menthol activate transient …
physiological condition, low to moderate concentrations of menthol activate transient …