KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury

JD Lai, JE Berlind, G Fricklas, C Lie, JP Urenda, K Lam… - Cell Stem Cell, 2024 - cell.com
Traumatic brain injury (TBI) strongly correlates with neurodegenerative disease. However, it
remains unclear which neurodegenerative mechanisms are intrinsic to the brain and which …

Injurious falls before, during and after dementia diagnosis: a population-based study

L Zhang, J Wang, A Dove, W Yang, X Qi… - Age and ageing, 2022 - academic.oup.com
Background the timing of incident injurious falls at different stages of dementia diagnosis is
unclear. Objectives to identify when the occurrence of injurious falls begins to increase …

Associations between traumatic brain injury and cognitive decline among older male veterans: A twin study

M Chanti-Ketterl, CF Pieper, K Yaffe, BL Plassman - Neurology, 2023 - AAN Enterprises
Background and Objectives Traumatic brain injuries (TBIs) are associated with increased
risk of dementia, but whether lifetime TBI influences cognitive trajectories in later life is less …

Blunt traumatic brain injury and alzheimer pathology

KA Jellinger - Dementia and geriatric cognitive disorders, 2023 - karger.com
Introduction: Traumatic brain injury (TBI) has been associated with a greater risk of late-life
dementia, including Alzheimer's disease (AD), but only a few studies examined the …

Single episode of moderate to severe traumatic brain injury leads to chronic neurological deficits and Alzheimer's-like pathological dementia

K Vaibhav, M Gulhane, P Ahluwalia, M Kumar… - GeroScience, 2024 - Springer
Traumatic brain injury (TBI) is one of the foremost causes of disability and mortality globally.
While the scientific and medical emphasis is to save lives and avoid disability during acute …

In vivo Examination of Peripheral Drivers of Alzheimer's Disease

C Catumbela - 2024 - digitalcommons.library.tmc.edu
Alzheimer's disease (AD) is the leading cause of dementia worldwide, and predominantly
affects elderly populations. This disease is well known for its effects on the brain, but a …