Endothelial microparticles in diseases

GN Chironi, CM Boulanger, A Simon… - Cell and tissue …, 2009 - Springer
Microparticles are submicron vesicles shed from plasma membranes in response to cell
activation, injury, and/or apoptosis. The measurement of the phospholipid content (mainly …

[HTML][HTML] Circulating microparticles in cardiovascular disease: implications for atherogenesis and atherothrombosis

E Shantsila, PW Kamphuisen, GYH Lip - Journal of Thrombosis and …, 2010 - Elsevier
The complex and multifactorial nature of atherogenesis and development of
atherothrombotic complications involves numerous interactions between various cell types …

Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers

C Gordon, K Gudi, A Krause, R Sackrowitz… - American journal of …, 2011 - atsjournals.org
Rationale: There is increasing evidence that emphysema is associated with primary loss of
pulmonary capillary endothelium. Plasma levels of endothelial microparticles (EMPs), small …

A framework of biomarkers for vascular aging: a consensus statement by the Aging Biomarker Consortium

Aging Biomarker Consortium, L Zhang, J Guo… - Life …, 2023 - academic.oup.com
Aging of the vasculature, which is integral to the functioning of literally all human organs,
serves as a fundamental physiological basis for age-related alterations as well as a shared …

[HTML][HTML] Antigenic characterization of endothelial cell-derived microparticles and their detection ex vivo

MNA Hussein, EW Meesters, N Osmanovic… - Journal of Thrombosis …, 2003 - Elsevier
Background: Endothelial activation and dysfunction are associated with several diseases.
However, hardly any specific markers are available. Microparticles (MP) from endothelial …

Effect of intensive periodontal therapy on blood pressure and endothelial microparticles in patients with prehypertension and periodontitis: a randomized controlled …

QB Zhou, WH Xia, J Ren, BB Yu, XZ Tong… - Journal of …, 2017 - Wiley Online Library
Background: Although some studies show a positive association between periodontitis and
blood pressure (BP) elevation, research on the effect of intensive periodontal treatment on …

Circulating endothelial and platelet derived microparticles reflect the size of myocardium at risk in patients with ST-elevation myocardial infarction

C Jung, P Sörensson, N Saleh, H Arheden, L Rydén… - Atherosclerosis, 2012 - Elsevier
OBJECTIVES: Microparticles (MP) are small membrane vesicles, released from activated,
damaged and apoptotic endothelial cells (EMP) or platelets (PMP) that may actively …

Microparticles in multiple sclerosis and clinically isolated syndrome: effect on endothelial barrier function

B Marcos-Ramiro, P Oliva Nacarino… - BMC neuroscience, 2014 - Springer
Background Cell-derived microparticles are secreted in response to cell damage or
dysfunction. Endothelial and platelet dysfunction are thought to contribute to the …

Increased levels of microparticles originating from endothelial cells, platelets and erythrocytes in subjects with metabolic syndrome: relationship with oxidative stress

O Helal, C Defoort, S Robert, C Marin, N Lesavre… - Nutrition, Metabolism …, 2011 - Elsevier
BACKGROUND AND AIMS: The Metabolic Syndrome (MetS) is associated with increased
cardiovascular risk. Circulating microparticles (MP) are involved in the pathogenesis of …

Isolation and primary culture of mouse aortic endothelial cells

JM Wang, AF Chen, K Zhang - Journal of visualized …, 2016 - pmc.ncbi.nlm.nih.gov
The vascular endothelium is essential to normal vascular homeostasis. Its dysfunction
participates in various cardiovascular disorders. The mouse is an important model for …