Abstract This is a Brighton Collaboration Case Definition of the term “Multisystem
Inflammatory Syndrome in Children and Adults (MIS-C/A)” to be utilized in the evaluation of …

Immune checkpoint inhibitors have proven to be efficacious for a broad spectrum of solid
organ malignancies. These monoclonal antibodies lead to cytotoxic T-cell activation and …

Background Cases of severe drug hypersensitivity, demonstrating a variable spectrum of
cutaneous and systemic involvement, are reported under various names, especially drug …

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, also referred to
as drug-induced hypersensitivity syndrome, is a distinct, potentially life-threatening adverse …

Drug reaction with eosinophilia and systemic symptoms, known by its acronym in English as
DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms), clinically manifests with …

When questioned, about 10% of the parents report suspected hypersensitivity to at least one
drug in their children. However, only a few of these reactions can be confirmed as allergic …

Despite significant improvements in leprosy (Hansen's disease) treatment and outlook for
patients since the introduction of multidrug therapy (MDT) 3 decades ago, the global …

Valproic acid is a widely-used first-generation antiepileptic drug, prescribed predominantly
in epilepsy and psychiatric disorders. VPA has good efficacy and pharmacoeconomic …

Pharmaceutical agents provide diagnostic and therapeutic utility that are central to patient
care. However, all agents also carry adverse drug effect profiles. While most of these are …

Idiosyncratic drug reactions are a significant cause of morbidity and mortality for patients;
they also markedly increase the uncertainty of drug development. The major targets are skin …