Design Principles of DNA-Barcodes for Nanopore-FET Readout, Based on Molecular Dynamics and TCAD Simulations

A Voorspoels, J Gevers, S Santermans… - The Journal of …, 2024 - ACS Publications
Nanopore field-effect transistor (NP-FET) devices hold great promise as sensitive single-
molecule sensors, which provide CMOS-based on-chip readout and are also highly …

Nanopore Field-Effect Transistors for Single-Protein Detection: Design and Operation Optimization via Compact Modeling

N Akkan, K Willems, K Martens… - IEEE Sensors …, 2024 - ieeexplore.ieee.org
Nanopore-based direct detection of single proteins represents a highly promising, yet
complex, area of research, primarily due to the rapid translocation of proteins, which …

High-Throughput Nanopore-FET Array Readout IC With 5-MHz Bandwidth and Background Offset/Drift Calibration

A Das, Q Lin, S Santermans, L Liu… - … on Circuits and …, 2023 - ieeexplore.ieee.org
This paper presents a high-speed readout interface suitable for nanopore-FET (NPFET)
sensor arrays, which are being explored for high-throughput DNA or protein sequencing …

Detectability limits of single proteins with nanopore-based voltage and ionic-current sensing

N Akkan, K Martens, G Gielen… - 2024 IEEE European …, 2024 - ieeexplore.ieee.org
Nanopore-based direct detection of single proteins is a promising yet challenging research
topic due to the fast translocation of proteins, especially when compared to DNA-based …

Integration of solid-state nanopore arrays via dry bonding to photostructured microfluidic networks

PD Jones, M Mierzejewski - arXiv preprint arXiv:2409.13394, 2024 - arxiv.org
The integration and parallelization of nanopore sensors are essential for improving the
throughput of nanopore measurements. Solid-state nanopores traditionally have been used …

Detecting translocation of DNA nanostructures through nanopores: first steps towards structural barcode readout

P Upretee, S Santermans, K Martens… - 2023 31st European …, 2023 - ieeexplore.ieee.org
Nanopore sequencing works on the principle of detecting the patterns in the current as a
biomolecule translocates through an electrically charged nanopore. Robustly detecting such …