Cucurbitacin II a: A review of phytochemistry and pharmacology

Y Zeng, J Wang, Q Huang, Y Ren, T Li… - Phytotherapy …, 2021 - Wiley Online Library
Cucurbitacin IIa was first found in plants and it belongs to tetracyclo triterpenoids. It is one of
the most important active components in cucurbitaceae plants. Studies have found that …

Anticancer activity of silver nanoparticles from Panax ginseng fresh leaves in human cancer cells

V Castro-Aceituno, S Ahn, SY Simu, P Singh… - Biomedicine & …, 2016 - Elsevier
The pharmaceutical role of silver nanoparticles has been increased over the last decades,
especially those synthesized through herbal medicinal plants, due to their variety of …

Cellular migration and invasion uncoupled: increased migration is not an inexorable consequence of epithelial-to-mesenchymal transition

D Schaeffer, JA Somarelli, G Hanna… - … and cellular biology, 2014 - Taylor & Francis
Metastatic dissemination requires carcinoma cells to detach from the primary tumor and
invade through the basement membrane. To acquire these characteristics, epithelial tumor …

Autocrine signaling via release of ATP and activation of P2X7 receptor influences motile activity of human lung cancer cells

E Takai, M Tsukimoto, H Harada, S Kojima - Purinergic signalling, 2014 - Springer
Extracellular nucleotides, such as ATP, are released from cells and play roles in various
physiological and pathological processes through activation of P2 receptors. Here, we show …

Effects of different ligands on epidermal growth factor receptor (EGFR) nuclear translocation

JAQA Faria, C de Andrade, AM Goes… - Biochemical and …, 2016 - Elsevier
The epidermal growth factor receptor (EGFR) is activated through binding to specific ligands
and generates signals for proliferation, differentiation, migration, and cell survival. Recent …

Nuclear pyruvate kinase M2 (PKM2) contributes to phosphoserine aminotransferase 1 (PSAT1)-mediated cell migration in EGFR-activated lung cancer cells

R Biyik-Sit, T Kruer, S Dougherty, JA Bradley… - Cancers, 2021 - mdpi.com
Simple Summary Alternative functions for metabolic proteins have recently been shown to
drive cancer growth. These may include differential enzymatic activity or novel protein …

[HTML][HTML] NSCLC presents metabolic heterogeneity, and there is still some leeway for EGF stimuli in EGFR-mutated NSCLC

C Mendes, I Lemos, I Francisco, T Almodôvar, F Cunha… - Lung Cancer, 2023 - Elsevier
Background Metabolic remodeling is crucial in carcinogenesis and cancer progression.
Oncogenic mutations may promote metabolic reprogramming in cancer cells to support their …

Sulfated polysaccharide of Sepiella Maindroni ink inhibits the migration, invasion and matrix metalloproteinase-2 expression through suppressing EGFR-mediated …

W Jiang, Y Cheng, N Zhao, L Li, Y Shi, A Zong… - International journal of …, 2018 - Elsevier
Previous studies demonstrated that SIP-SII, a sulfated derivative of SIP that is isolated from
the ink of Sepiella maindroni, showed significant inhibition of tumor growth and metastasis …

3D printed inserts for reproducible high throughput screening of cell migration

AS Joshi, M Madhusudanan, I Mijakovic - Frontiers in Cell and …, 2023 - frontiersin.org
Cell migration is a fundamental and complex phenomenon that occurs in normal physiology
and in diseases like cancer. Hence, understanding cell migration is very important in the …

Silver nanoparticles from Dendropanax morbifera Léveille inhibit cell migration, induce apoptosis, and increase generation of reactive oxygen species in A549 lung …

V Castro Aceituno, S Ahn, SY Simu, C Wang… - In Vitro Cellular & …, 2016 - Springer
Green synthesized silver nanoparticles have significant potential in the pharmaceutical field
because of their biological functions such as antioxidant and anticancer activities. Novel …