Heart and blood vessels disorders comprise one of the main causes of death worldwide.
Pharmacologically active natural compounds have been used as a complementary therapy …

Calorie restriction (CR), a nutritional intervention of reduced energy intake but with adequate
nutrition, has been shown to extend healthspan and lifespan in rodent and primate models …

Caloric restriction (CR) without malnutrition extends lifespan and delays the onset of age-
related disorders in most species but its impact in nonhuman primates has been …

Objective Development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and the American College of …

A growing body of evidence indicates that time restricted feeding (TRF), a popular form of
intermittent fasting, can activate similar biological pathways as caloric restriction, the only …

Background Caloric restriction (CR), energy intake reduced below ad libitum (AL) intake,
increases life span in many species. The implications for humans can be clarified by …

A long-standing association exists between elevated triglyceride levels and cardiovascular
disease*(CVD). 1, 2 However, the extent to which triglycerides directly promote CVD or …

Restricting the intake of calories has been practiced as a method for increasing both the
length and quality of life for over 500years. Experimental work confirming the success of this …

Blood lipoproteins are formed by various amounts of cholesterol (C), triglycerides (TGs),
phospholipids, and apolipoproteins (Apos). ApoA1 is the major structural protein of high …

Hypertriglyceridemia is a prevalent risk factor for cardiovascular disease (CVD) and
increasingly important in the setting of current obesity and insulin resistance epidemics …