Multi-modal neuroimaging feature selection with consistent metric constraint for diagnosis of Alzheimer's disease

X Hao, Y Bao, Y Guo, M Yu, D Zhang, SL Risacher… - Medical image …, 2020 - Elsevier
The accurate diagnosis of Alzheimer's disease (AD) and its early stage, eg, mild cognitive
impairment (MCI), is essential for timely treatment or possible intervention to slow down AD …

Four distinct subtypes of Alzheimer's disease based on resting-state connectivity biomarkers

P Chen, H Yao, BM Tijms, P Wang, D Wang, C Song… - Biological …, 2023 - Elsevier
Background Alzheimer's disease (AD) is a neurodegenerative disorder with significant
heterogeneity. Different AD phenotypes may be associated with specific brain network …

Independent and reproducible hippocampal radiomic biomarkers for multisite Alzheimer's disease: diagnosis, longitudinal progress and biological basis

K Zhao, Y Ding, Y Han, Y Fan, AF Alexander-Bloch… - Science Bulletin, 2020 - Elsevier
Hippocampal morphological change is one of the main hallmarks of Alzheimer's disease
(AD). However, whether hippocampal radiomic features are robust as predictors of …

Generalizable, reproducible, and neuroscientifically interpretable imaging biomarkers for Alzheimer's disease

D Jin, B Zhou, Y Han, J Ren, T Han, B Liu… - Advanced …, 2020 - Wiley Online Library
Precision medicine for Alzheimer's disease (AD) necessitates the development of
personalized, reproducible, and neuroscientifically interpretable biomarkers, yet despite …

Hybrid federated learning with brain-region attention network for multi-center Alzheimer's disease detection

B Lei, Y Liang, J Xie, Y Wu, E Liang, Y Liu, P Yang… - Pattern Recognition, 2024 - Elsevier
Identifying reproducible and interpretable biomarkers for Alzheimer's disease (AD) detection
remains a challenge. AD detection using multi-center datasets can expand the sample size …

Altered global signal topography in Alzheimer's disease

P Chen, K Zhao, H Zhang, Y Wei, P Wang, D Wang… - Ebiomedicine, 2023 - thelancet.com
Background Alzheimer's disease (AD) is a neurodegenerative disease associated with
widespread disruptions in intrinsic local specialization and global integration in the …

Grab‐AD: generalizability and reproducibility of altered brain activity and diagnostic classification in Alzheimer's disease

D Jin, P Wang, A Zalesky, B Liu, C Song… - Human Brain …, 2020 - Wiley Online Library
Alzheimer's disease (AD) is associated with disruptions in brain activity and networks.
However, there is substantial inconsistency among studies that have investigated functional …

Application of structural and functional connectome mismatch for classification and individualized therapy in Alzheimer disease

H Ren, J Zhu, X Su, S Chen, S Zeng, X Lan… - Frontiers in public …, 2020 - frontiersin.org
While machine learning approaches to analyzing Alzheimer disease connectome
neuroimaging data have been studied, many have limited ability to provide insight in …

Characterizing white matter connectivity in Alzheimer's disease and mild cognitive impairment: An automated fiber quantification analysis with two independent …

X Dou, H Yao, F Feng, P Wang, B Zhou, D Jin, Z Yang… - Cortex, 2020 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by
progressive dementia. Diffusion tensor imaging (DTI) has been widely used to show …

Quantitative radiomic features as new biomarkers for Alzheimer's disease: An amyloid PET study

Y Ding, K Zhao, T Che, K Du, H Sun, S Liu… - Cerebral …, 2021 - academic.oup.com
Growing evidence indicates that amyloid-beta (Aβ) accumulation is one of the most common
neurobiological biomarkers in Alzheimer's disease (AD). The primary aim of this study was …