Roles of IFN-γ in tumor progression and regression: a review
D Jorgovanovic, M Song, L Wang, Y Zhang - Biomarker research, 2020 - Springer
Background Interferon-γ (IFN-γ) plays a key role in activation of cellular immunity and
subsequently, stimulation of antitumor immune-response. Based on its cytostatic, pro …
subsequently, stimulation of antitumor immune-response. Based on its cytostatic, pro …
Thermal immuno-nanomedicine in cancer
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …
promoting antitumour immunity in patients with tumours that are resistant to these therapies …
Rheumatoid arthritis and depression: an inflammatory perspective
L Nerurkar, S Siebert, IB McInnes… - The Lancet Psychiatry, 2019 - thelancet.com
The coexistence of immune-mediated inflammatory diseases with depression has long been
recognised. Data that illustrate the intimate associations between peripheral and brain …
recognised. Data that illustrate the intimate associations between peripheral and brain …
Nanoscale metal–organic frameworks for cancer immunotherapy
Conspectus Cancer immunotherapy, particularly checkpoint blockade immunotherapy (CBI),
has revolutionized the treatment of some cancers by reactivating the antitumor immunity of …
has revolutionized the treatment of some cancers by reactivating the antitumor immunity of …
Mining the microbiota for microbial and metabolite-based immunotherapies
Trillions of microorganisms transit through and reside in the mammalian gastrointestinal tract
each day, collectively producing thousands of small molecules and metabolites with local …
each day, collectively producing thousands of small molecules and metabolites with local …
Tryptophan catabolites from microbiota engage aryl hydrocarbon receptor and balance mucosal reactivity via interleukin-22
Endogenous tryptophan (Trp) metabolites have an important role in mammalian gut immune
homeostasis, yet the potential contribution of Trp metabolites from resident microbiota has …
homeostasis, yet the potential contribution of Trp metabolites from resident microbiota has …
[HTML][HTML] Indoleamine 2, 3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
M Gargaro, G Scalisi, G Manni, CG Briseño, P Bagadia… - Immunity, 2022 - cell.com
Conventional dendritic cells (cDCs), cDC1 and cDC2, act both to initiate immunity and
maintain self-tolerance. The tryptophan metabolic enzyme indoleamine 2, 3-dioxygenase 1 …
maintain self-tolerance. The tryptophan metabolic enzyme indoleamine 2, 3-dioxygenase 1 …
CTLA-4: From mechanism to autoimmune therapy
A Hosseini, T Gharibi, F Marofi, Z Babaloo… - International …, 2020 - Elsevier
CD28 and CTLA-4 are both important stimulatory receptors for the regulation of T cell
activation. Because receptors share common ligands, B7. 1 and B7. 2, the expression and …
activation. Because receptors share common ligands, B7. 1 and B7. 2, the expression and …
The role of decidual immune cells on human pregnancy
The maternal-fetal interface undergoes dynamic changes to allow the fetus to grow and
develop in the uterus, despite being recognized by the maternal immune cells. Within the …
develop in the uterus, despite being recognized by the maternal immune cells. Within the …
Commensal bacteria at the interface of host metabolism and the immune system
JR Brestoff, D Artis - Nature immunology, 2013 - nature.com
The mammalian gastrointestinal tract, the site of digestion and nutrient absorption, harbors
trillions of beneficial commensal microbes from all three domains of life. Commensal …
trillions of beneficial commensal microbes from all three domains of life. Commensal …