Importance Survival from sepsis has improved in recent years, resulting in an increasing
number of patients who have survived sepsis treatment. Current sepsis guidelines do not …

Sepsis has been identified by the World Health Organization (WHO) as a global health
priority. There has been a tremendous effort to decipher underlying mechanisms …

Objective To identify research priorities in the management, epidemiology, outcome and
underlying causes of sepsis and septic shock. Design A consensus committee of 16 …

Sepsis is a major cause of death in intensive care units worldwide. The acute phase of
sepsis is often accompanied by sepsis-associated encephalopathy, which is highly …

This is the eighteenth global report on tuberculosis (TB) published by WHO in a series that
started in 1997. It provides a comprehensive and up-to-date assessment of the TB epidemic …

PICS is defined as new or worsening impairment in physical, cognitive, or mental health
status arising and persisting after hospitalization for critical illness (Fig. 1)(1). Study results …

Sepsis-associated encephalopathy is a severe neurologic syndrome characterized by a
diffuse dysfunction of the brain caused by sepsis. This review provides a concise overview of …

This article is one of ten reviews selected from the Annual Update in Intensive Care and
Emergency Medicine 2017. Other selected articles can be found online at http://ccforum …

Background Survivors of sepsis must often endure significant cognitive and behavioral
impairments after discharge, but research on the relevant mechanisms and interventions …

Sepsis-associated brain dysfunction (SABD) may be the most common type of
encephalopathy in critically ill patients. SABD develops in up to 70% of septic patients and …