Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered
in bone marrow, are multipotent cells capable of differentiating into mature cells of several …

The balance between bone resorption and bone formation is vital for maintenance and
regeneration of alveolar bone and supporting structures around teeth and dental implants …

Implantation of stem cells for tissue regeneration faces significant challenges such as
immune rejection and teratoma formation. Cell‐free tissue regeneration thus has a potential …

Bone injuries and diseases constitute a burden both socially and economically, as the
consequences of a lack of effective treatments affect both the patients' quality of life and the …

Human mesenchymal stem cell (hMSC)-derived exosomes have shown regenerative
effects, but their role in osteogenesis and the underlying mechanism are yet to be …

The effective regeneration of weight‐bearing bone defects and critical‐sized cartilage
defects remains a significant clinical challenge. Traditional treatments such as autologous …

Introduction: MicroRNAs (miRNAs) has emerged as important factors in osteogenesis and
chondrogenesis. This study aimed to determine whether miR-221 is involved in the …

Abstract Globally, more than 1.5 million patients undergo bone graft surgeries annually, and
the development of biomaterial scaffolds that mimic natural bone for bone grafting remains a …

Abstract Background MicroRNAs (miRNAs or miRs) serve crucial roles in the progression of
osteoporosis. This study investigated the role and specific molecular mechanism of miR-135 …

Bone defects caused by injury, disease, or congenital deformity remain a major health
concern, and efficiently regenerating bone is a prominent clinical demand worldwide …