Background: The Religious Orders Study and Rush Memory and Aging Project are both
ongoing longitudinal clinical-pathologic cohort studies of aging and Alzheimer's disease …

In contrast to traditional perspectives of resilience as a stable, trait-like characteristic,
resilience is now recognized as a multidimentional, dynamic capacity influenced by life-long …

Importance Neuropsychiatric symptoms, depressive symptoms in particular, are common in
patients with dementia but whether depressive symptoms in adulthood increases the risk for …

Depression is highly common throughout the life course and dementia is common in late life.
Depression has been linked with dementia, and growing evidence implies that the timing of …

The Memory and Aging Project is a longitudinal, epidemiologic clinical-pathologic cohort
study of common chronic conditions of aging with an emphasis on decline in cognitive and …

The past several decades have witnessed unidimensional decline models of aging give way
to life-span developmental models that consider how specific processes and strategies …

In this monograph, we ask whether various kinds of intellectual, physical, and social
activities produce cognitive enrichment effects—that is, whether they improve cognitive …

Background Circadian disturbances are commonly seen in people with Alzheimer's disease
and have been reported in individuals without symptoms of dementia but with Alzheimer's …

Background Few prospective studies have assessed diabetes mellitus as a risk factor for
incident Alzheimer disease (AD) and decline in cognitive function. Objective To evaluate the …

Research indicates that after advanced age, the major risk factor for late-onset Alzheimer's
disease is female sex. Out of every three AD patients, two are females with postmenopausal …