Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome

BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …

In silico investigation and potential therapeutic approaches of natural products for COVID-19: Computer-aided drug design perspective

MM Rahman, MR Islam, S Akash, SA Mim… - Frontiers in Cellular …, 2022 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a
substantial number of deaths around the world, making it a serious and pressing public …

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients

J Hadjadj, N Yatim, L Barnabei, A Corneau, J Boussier… - Science, 2020 - science.org
Coronavirus disease 2019 (COVID-19) is characterized by distinct patterns of disease
progression that suggest diverse host immune responses. We performed an integrated …

Natural killer cell immunotypes related to COVID-19 disease severity

C Maucourant, I Filipovic, A Ponzetta, S Aleman… - Science …, 2020 - science.org
Understanding innate immune responses in coronavirus disease 2019 (COVID-19) is
important to decipher mechanisms of host responses and interpret disease pathogenesis …

Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome

D Weiskopf, KS Schmitz, MP Raadsen, A Grifoni… - Science …, 2020 - science.org
SARS-CoV-2 has been identified as the causative agent of a global outbreak of respiratory
tract disease (COVID-19). In some patients, the infection results in moderate to severe acute …

The relationship among fear and anxiety of COVID‐19, pregnancy experience, and mental health disorder in pregnant women: A structural equation model

L Salehi, M Rahimzadeh, E Molaei, H Zaheri… - Brain and …, 2020 - Wiley Online Library
Introduction Coronavirus pandemic causes stress and anxiety for pregnant women
worldwide. The present study was conducted for the path analysis of the relationship among …

Inflammatory profiles across the spectrum of disease reveal a distinct role for GM-CSF in severe COVID-19

RS Thwaites, A Sanchez Sevilla Uruchurtu… - Science …, 2021 - science.org
While it is now widely accepted that host inflammatory responses contribute to lung injury,
the pathways that drive severity and distinguish coronavirus disease 2019 (COVID-19) from …

SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19

JA Perez-Bermejo, S Kang, SJ Rockwood… - Science translational …, 2021 - science.org
Although coronavirus disease 2019 (COVID-19) causes cardiac dysfunction in up to 25% of
patients, its pathogenesis remains unclear. Exposure of human induced pluripotent stem cell …

Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19

ER Mann, M Menon, SB Knight, JE Konkel… - Science …, 2020 - science.org
COVID-19 pathogenesis is associated with an exaggerated immune response. However, the
specific cellular mediators and inflammatory components driving diverse clinical disease …

Inflammasome activation in neutrophils of patients with severe COVID-19

K Aymonnier, J Ng, LE Fredenburgh… - Blood …, 2022 - ashpublications.org
Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) engages
the inflammasome in monocytes and macrophages and leads to the cytokine storm in …