Cancer is a deadly disease with complicated pathology. Present chemotherapy regimen
encounters challenges such as cytotoxicity, non-specificity and development of drug …

Simple Summary Since it was first described over two decades ago, the Alternative
Lengthening of Telomeres (ALT) pathway has been well accepted to hold clinical …

Abstract Objective Standard DSC-PWI analyses are based on concrete parameters and
values, but an approach that contemplates all points in the time-intensity curves and all …

Long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1
(MALAT1) has been shown to play a critical role in the development of several …

Brain tumor represents one of the most fatal cancers around the world, and is very common
in children and the elderly. Accurate identification of the type and grade of tumor in the early …

Objectives To evaluate the performance of multiparametric neurite orientation dispersion
and density imaging (NODDI) radiomics in distinguishing between glioblastoma (Gb) and …

BACKGROUND AND PURPOSE: DSC-PWI has demonstrated promising results in the
presurgical diagnosis of brain tumors. While most studies analyze specific parameters …

Our understanding of intratumoral heterogeneity in cancer continues to evolve, with current
models incorporating single-cell signatures to explore cell–cell interactions and …

Gliomas represent 80% of all primary malignant brain tumors in adults. In view of this public
health problem, the early detection through sensitive and specific molecular tumor markers …

Background Standard follow-up care for patients with high-grade glioma (HGG) involves
routine surveillance imaging to detect disease progression, assess treatment response, and …