Autosomal dominant non-syndromic hearing loss (HL) typically occurs when only one
dominant allele within the disease gene is sufficient to express the phenotype. Therefore …

From the first identified non-syndromic hearing loss gene in 1995, to those discovered in
present day, the field of human genetics has witnessed an unparalleled revolution that …

The DNA-binding protein REST forms complexes with histone deacetylases (HDACs) to
repress neuronal genes in non-neuronal cells. In differentiating neurons, REST is …

Genetic hearing loss crosses almost all the categories of hearing loss which includes the
following: conductive, sensory, and neural; syndromic and nonsyndromic; congenital …

Neuroplasticity is a crucial property of the central nervous system to change its activity in
response to intrinsic or extrinsic stimuli. This is mainly achieved through the promotion of …

Tinnitus is a prevalent condition in which perception of sound occurs without an external
stimulus. It is often associated with pre-existing hearing loss or noise-induced damage to the …

Therapeutic strategies to restore hearing and balance in mouse models of inner ear disease
aim to rescue sensory function by gene replacement, augmentation, knock down or knock …

Disabling hearing loss is expected to affect over 900 million people worldwide by 2050. The
World Health Organization estimates that the annual economic impact of hearing loss …

Literature and clinical practice around adult‐onset hearing loss (HL) has traditionally
focused on environmental risk factors, including noise exposure, ototoxic drug exposure …

Jones syndrome is a rare dominantly inherited syndrome characterized by gingival
fibromatosis and progressive sensorineural hearing loss becoming symptomatic in the …