Fighting age-related orthopedic diseases: focusing on ferroptosis

Q Ru, Y Li, W Xie, Y Ding, L Chen, G Xu, Y Wu… - Bone research, 2023 - nature.com
Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation
and lipid peroxidation. It is closely related to multiple biological processes, including iron …

A scoping review of the skeletal effects of naringenin

ML Nor Muhamad, SO Ekeuku, SK Wong, KY Chin - Nutrients, 2022 - mdpi.com
Background: Osteoporosis is caused by the deterioration of bone density and microstructure,
resulting in increased fracture risk. It transpires due to an imbalanced skeletal remodelling …

Flavonoid extract from propolis alleviates periodontitis by boosting periodontium regeneration and inflammation resolution via regulating TLR4/MyD88/NF-κB and …

M Tang, G Wang, J Li, Y Wang, C Peng… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance In traditional Chinese medicine, propolis has
been used for treating oral diseases for centuries, widely. Flavonoid extract is the main …

Design, synthesis, molecular docking, molecular dynamic simulation, and MMGBSA analysis of 7-O-substituted 5-hydroxy flavone derivatives

KB Patel, RV Patel, I Ahmad, D Rajani… - Journal of …, 2024 - Taylor & Francis
A series of chrysin derivatives were designed, synthesized, and evaluated for their
antibacterial activity against four different bacterial strains. We have synthesized new propyl …

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss

PA Jayusman, NS Nasruddin, B Baharin… - Frontiers in …, 2023 - frontiersin.org
Osteoporosis and periodontitis are two major chronic diseases of postmenopausal women.
The association between these two diseases are evident through systemic bone loss and …

Chrysin, a 5, 7-dihydroxyflavone restrains inflammatory arthritis in rats via subsiding oxidative stress biomarkers and inflammatory cytokines

A Afnan, A Saleem, MF Akhtar - Inflammopharmacology, 2023 - Springer
This study was intended to appraise the anti-inflammatory and anti-arthritic potential of
Chrysin (CR), a natural dietary flavone found in several plant genera, including Passiflora …

Royal Jelly: Biological Action and Health Benefits

N Oršolić, M Jazvinšćak Jembrek - International Journal of Molecular …, 2024 - mdpi.com
Royal jelly (RJ) is a highly nutritious natural product with great potential for use in medicine,
cosmetics, and as a health-promoting food. This bee product is a mixture of important …

Extraction technology, components analysis and anti-inflammatory activity in vitro of total flavonoids extract from Artemisia anomala S. Moore

Y Shao, R Hong, B Li, A Wang, Y Chen, Y Wang, F Mo… - Fitoterapia, 2023 - Elsevier
Artemisia anomala S. Moore exerts many pharmacological activities, including the removing
of the blood stasis, relieving of the fever and analgesia, reducing the swelling and …

Chrysin is immunomodulatory and anti-inflammatory against complete Freund's adjuvant-induced arthritis in a pre-clinical rodent model

MA Faheem, T Akhtar, N Naseem, U Aftab, MS Zafar… - Pharmaceutics, 2023 - mdpi.com
Chrysin (5, 7-dihydroxyflavone) has many pharmacological properties including anti-
inflammatory actions. The objective of this study was to evaluate the anti-arthritic activity of …

The alleviative efficacy of sildenafil and chrysin against zinc oxide nanoparticles-provoked hepatic and blood toxicity: role of MyD88/NF-κB1/TNF-α pathway

MM Nageeb, MAM Amer, DM Hendawy… - Beni-Suef University …, 2023 - Springer
Background Zinc oxide nanoparticles are nanoparticles of metal oxide with semiconductor
properties and proved many noxious effects on the mammalian cell. Sildenafil, a …