Background and aim Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory
disease; the clinical manifestations are correlated with continuum multiarticular synovitis …

Neuroinflammation is an inflammatory response in the brain and spinal cord, which can
involve the activation of microglia and astrocytes. It is a common feature of many central …

Frontotemporal dementia (FTD) refers to a group of progressive neurodegenerative
disorders with different pathological signatures, genetic variability and complex disease …

Fibromyalgia (FM) is a poorly understood chronic condition characterized by widespread
musculoskeletal pain, fatigue, and cognitive difficulties. While mounting evidence suggests a …

BackgroundConverging lines of evidence implicate an important role for the immune system
in schizophrenia. Microglia are the resident immune cells of the central nervous system and …

The translocator protein (TSPO) is an outer mitochondrial membrane protein that is widely
used as a biomarker of neuroinflammation, being markedly upregulated in activated …

The 18 kDa translocator protein (TSPO) is increasingly used to study brain and spinal cord
inflammation in degenerative diseases of the CNS such as multiple sclerosis. The enhanced …

Neuroinflammation is a significant contributor to Alzheimer's disease (AD). Until now, PET
imaging of the translocator protein (TSPO) has been widely used to depict the neuroimmune …

Background Accumulating evidence suggests that the immune system may be an important
target for new treatment approaches in schizophrenia. Positron emission tomography and …

In the last decade, positron emission tomography (PET) and single-photon emission
computed tomography (SPECT) in in vivo imaging has attempted to demonstrate the …