Antibacterial nanomaterials: mechanisms, impacts on antimicrobial resistance and design principles

M Xie, M Gao, Y Yun, M Malmsten… - Angewandte Chemie …, 2023 - Wiley Online Library
Antimicrobial resistance (AMR) is one of the biggest threats to the environment and health.
AMR rapidly invalidates conventional antibiotics, and antimicrobial nanomaterials have …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Synergistic antibacterial strategy based on photodynamic therapy: Progress and perspectives

X Hu, H Zhang, Y Wang, BC Shiu, JH Lin… - Chemical Engineering …, 2022 - Elsevier
The dramatic increase in drug resistant bacteria resistance to existing conventional
antibiotics poses a great challenge to the effective treatment of infectious diseases …

Emerging photothermal-derived multimodal synergistic therapy in combating bacterial infections

J Huo, Q Jia, H Huang, J Zhang, P Li, X Dong… - Chemical Society …, 2021 - pubs.rsc.org
Due to the emerging bacterial resistance and the protection of tenacious biofilms, it is hard
for the single antibacterial modality to achieve satisfactory therapeutic effects nowadays. In …

A bacteria‐responsive porphyrin for adaptable photodynamic/photothermal therapy

H Hu, H Wang, Y Yang, JF Xu, X Zhang - Angewandte Chemie, 2022 - Wiley Online Library
We report a cationic porphyrin 5, 10, 15, 20‐tetrakis‐(4‐N‐methylpyridyl)‐porphyrin (TMPyP)
that can respond to specific bacteria, followed by adaptable photodynamic/photothermal …

Organic photo-antimicrobials: Principles, molecule design, and applications

B Ran, Z Wang, W Cai, L Ran, W Xia… - Journal of the …, 2021 - ACS Publications
The emergence of multi-drug-resistant pathogens threatens the healthcare systems world-
wide. Recent advances in phototherapy (PT) approaches mediated by photo-antimicrobials …

Reactivity differences enable ROS for selective ablation of bacteria

X Wu, M Yang, JS Kim, R Wang, G Kim… - Angewandte …, 2022 - Wiley Online Library
An effective strategy to engineer selective photodynamic agents to surmount bacterial‐
infected diseases, especially Gram‐positive bacteria remains a great challenge. Herein, we …

Near-infrared photodynamic and photothermal co-therapy based on organic small molecular dyes

S Guo, D Gu, Y Yang, J Tian, X Chen - Journal of Nanobiotechnology, 2023 - Springer
Near-infrared (NIR) organic small molecule dyes (OSMDs) are effective photothermal agents
for photothermal therapy (PTT) due to their advantages of low cost and toxicity, good …

Supramolecular agents for combination of photodynamic therapy and other treatments

N Kwon, H Kim, X Li, J Yoon - Chemical Science, 2021 - pubs.rsc.org
Photodynamic therapy (PDT) is a promising treatment for cancers such as superficial skin
cancers, esophageal cancer, and cervical cancer. Unfortunately, PDT often does not have …

Photodynamic and photothermal therapies for bacterial infection treatment

H Kim, YR Lee, H Jeong, J Lee, X Wu, H Li… - Smart …, 2023 - Wiley Online Library
Bacteria can cause numerous infectious diseases and has been a major threat to human
humans. Although antibiotics have partially succeeded in treating bacteria, owing to …