Colorectal cancer (CRC) is often diagnosed at an advanced stage when tumor cell
dissemination has taken place. Chemo-and targeted therapies provide only a limited …

Tumor-infiltrating lymphocytes (TILs) are an important histopathologic feature of colorectal
cancer that confer prognostic information. Previous clinical and epidemiologic studies have …

Lynch syndrome, which is now recognized as the most common hereditary colorectal cancer
condition, is characterized by the predisposition to a spectrum of cancers, primarily …

Background: Tumour-infiltrating lymphocytes (TILs) are often found in tumours, presumably
reflecting an immune response against the tumour. We carried out a systematic review and …

Microsatellite instability (MSI) is a molecular marker of a deficient mismatch repair (MMR)
system and occurs in approximately 15% of colorectal cancers (CRCs), more frequently in …

Abstract The American Joint Committee on Cancer/Union Internationale Contre le Cancer
(AJCC/UICC) TNM staging system provides the most reliable guidelines for the routine …

Purpose: To determine whether the tumor immune infiltrate, as recently evaluated with the
Immunoscore methodology, could be a useful prognostic marker in patients with rectal …

Background Colorectal cancer (CRC) consensus molecular subtypes (CMS) have different
immunological, stromal cell, and clinicopathological characteristics. Single-cell …

Background: The role of tumour-infiltrating inflammation in the prognosis of patients with
colorectal cancer (CRC) has not been fully evaluated. The primary objective of our meta …

The abundance of tumour‐infiltrating T‐cells has been associated with microsatellite
instability (MSI) and a favourable prognosis in colorectal cancer. However, numerous …