Brillouin microscopy: an emerging tool for mechanobiology

R Prevedel, A Diz-Muñoz, G Ruocco, G Antonacci - Nature methods, 2019 - nature.com
The role and importance of mechanical properties of cells and tissues in cellular function,
development and disease has widely been acknowledged, however standard techniques …

Brillouin light scattering: applications in biomedical sciences

F Palombo, D Fioretto - Chemical reviews, 2019 - ACS Publications
Brillouin spectroscopy and imaging are emerging techniques in analytical science,
biophotonics, and biomedicine. They are based on Brillouin light scattering from acoustic …

Brillouin light scattering anisotropy microscopy for imaging the viscoelastic anisotropy in living cells

H Keshmiri, D Cikes, M Samalova, L Schindler… - Nature …, 2024 - nature.com
Maintaining and modulating mechanical anisotropy is essential for biological processes.
However, how this is achieved at the microscopic scale in living soft matter is not always …

Diagnostic potential of blood plasma longitudinal viscosity measured using Brillouin light scattering

J Illibauer, T Clodi-Seitz, A Zoufaly, JH Aberle… - Proceedings of the …, 2024 - pnas.org
Blood plasma viscosity (PV) is an established biomarker for numerous diseases.
Measurement of the shear PV using conventional rheological techniques is, however, time …

Mapping mechanical properties of biological materials via an add-on Brillouin module to confocal microscopes

J Zhang, G Scarcelli - Nature protocols, 2021 - nature.com
Several techniques have been developed over the past few decades to assess the
mechanical properties of biological samples, which has fueled a rapid growth in the fields of …

Excitation and detection of acoustic phonons in nanoscale systems

RC Ng, A El Sachat, F Cespedes, M Poblet, G Madiot… - Nanoscale, 2022 - pubs.rsc.org
Phonons play a key role in the physical properties of materials, and have long been a topic
of study in physics. While the effects of phonons had historically been considered to be a …

Imaging mechanical properties of sub-micron ECM in live zebrafish using Brillouin microscopy

C Bevilacqua, H Sánchez-Iranzo, D Richter… - Biomedical Optics …, 2019 - opg.optica.org
In this work, we quantify the mechanical properties of the extra-cellular matrix (ECM) in live
zebrafish using Brillouin microscopy. Optimization of the imaging conditions and …

Tissue biomechanics during cranial neural tube closure measured by Brillouin microscopy and optical coherence tomography

J Zhang, R Raghunathan, J Rippy, C Wu… - Birth defects …, 2019 - Wiley Online Library
Background Embryonic development involves the interplay of driving forces that shape the
tissue and the mechanical resistance that the tissue offers in response. While increasing …

Mechanical mapping of mammalian follicle development using Brillouin microscopy

CJ Chan, C Bevilacqua, R Prevedel - Communications biology, 2021 - nature.com
In early mammalian development, the maturation of follicles containing the immature
oocytes is an important biological process as the functional oocytes provide the bulk genetic …

Brillouin microscopy

I Kabakova, J Zhang, Y Xiang, S Caponi… - Nature Reviews …, 2024 - nature.com
The field of Brillouin microscopy and imaging was established approximately 20 years ago,
thanks to the development of non-scanning high-resolution optical spectrometers. Since …