Background The perception of effort provides information on task difficulty and influences
physical exercise regulation and human behavior. This perception differs from other …

In recent years, the continuous growth in global infectious disease coupled with population
growth and the associated increase in expectancy lead to the search for new ways of …

Exercise intolerance may be considered a hallmark in patients who suffer from heart failure
(HF) syndrome. Currently, there is enough scientific evidence regarding functional and …

Regardless of the management regime for heart failure (HF), there is strong evidence
supporting the early implementation of exercise-based cardiac rehabilitation (CR) …

Simple Summary This study aimed to elucidate whether exercise intolerance with muscle
blood flow restriction is located within the central nervous system or the heart, namely …

Background For the treatment of breathlessness in heart failure (HF), most textbooks
advocate the use of opioids. Yet, meta-analyses are lacking. Methods A systematic review …

Aim: Skeletal muscle convective and diffusive oxygen (O2) transport are peripheral
determinants of exercise capacity in both patients with chronic obstructive pulmonary …

Exercise intolerance and exertional dyspnoea are the cardinal symptoms of heart failure
with reduced ejection fraction (HFrEF). In HFrEF, abnormal autonomic and cardiopulmonary …

Mechanical and metabolic signals associated with skeletal muscle contraction stimulate the
sensory endings of thin fiber muscle afferents and produce reflex increases in sympathetic …

The study of natural computation for science, industry, commerce, and especially healthcare
systems has borne much fruit. Nature has proposed ways in which design spaces can be …