Helicobacter pylori (H. pylori) infection is associated with some gastric diseases, such as
gastritis, peptic ulcer, and gastric cancer. CagA and VacA are known virulence factors of H …

Helicobacter pylori (H. pylori) as a causative agent of gastric complications, is well adapted
for the colonization of gastric mucosa. Although the infectious process depends on several …

The mouse intestinal mucus is mainly made up by the gel-forming Muc2 mucin and the
stomach surface mucus Muc5ac, both extensively O-glycosylated. The oligosaccharide …

The mucin O-glycosylation of 10 individuals with and without gastric disease was examined
in depth in order to generate a structural map of human gastric glycosylation. In the stomach …

Glycosylation is the most frequent and structurally complex posttranslational modification in
cell-surface and secreted proteins. Glycans are major orchestrators of biological processes …

The human gut is inhabited by a large variety of microorganims involved in many
physiological processes and collectively referred as to gut microbiota. Disrupted microbiome …

Glycoconjugates and free glycan are involved in a variety of biological processes such as
cell–cell interaction and cell trafficking. Alterations in the complex glycosylation machinery …

Adhesion of Helicobacter pylori to the gastric mucosa is a necessary prerequisite for the
pathogenesis of H. pylori–related diseases. In this study, we investigated the GalNAcβ1 …

Highlights•Diversity of mucin glycans along the GI tract offers numerous recognition sites for
gut bacteria.•Commensal and pathogenic bacteria have evolved adhesins with …

An increasing number of studies have shown that the disaccharide GalNAcβ1→ 4GlcNAc
(LacdiNAc) group bound to N-and O-glycans in glycoproteins is expressed in a variety of …