Introduction Abnormal lipid metabolism, one of the hallmarks in cancer, has gradually
emerged as a novel target for cancer treatment. As organelles that store and release excess …

Elevated lipid metabolism is one of hallmarks of malignant tumors. Lipids not only serve as
essential structural components of biological membranes but also provide energy and …

Cannabinoid (CB) receptors (CB1 and CB2) are expressed on cancer cells and their
expression influences carcinogenesis in various tumor entities. Cells of the tumor …

Myeloperoxidase (MPO) is a neutrophil-derived enzyme that has been recently associated
with tumour development. However, the mechanisms by which this enzyme exerts its …

Sphingolipids are important for the physicochemical properties of cellular membranes and
deregulated in tumors. In human colon cancer tissue ceramide synthase (CerS) 4 and …

Rationale: Renal fibrosis, with no therapeutic approaches, is a common pathological feature
in various chronic kidney diseases (CKD). Tubular cell injury plays a pivotal role in renal …

We recently described that monoacylglycerol lipase (MGL) is present in the tumor
microenvironment (TME), increasing tumor growth. In this study we compare the implications …

Simple Summary The body's defense system, which comprises immune cells, is an
important factor contributing to tumor growth and treatment response. A “hot” tumor …

Numerous studies in various cancer models have demonstrated that ingredients of cannabis
can influence tumor growth through the endocannabinoid system (ECS), a network of …

Hepatocellular carcinoma (HCC) being a leading cause of cancer-related death, has high
associated mortality and recurrence rates. It has been of great necessity and urgency to find …