Probing drug-target engagement of soluble Gαi1 protein using the SolThermoBRET thermal shift assay

O Brod, D Plevako, T Perera, P Hompluem, EJ Koers… - bioRxiv, 2024 - biorxiv.org
Introduction: Sensitive protein stability assays used during hit confirmation conventionally
require high quantities of purified protein. Here, we describe a novel high-throughput 384 …