A rich array of prostate cancer molecular biomarkers: opportunities and challenges

I Kohaar, G Petrovics, S Srivastava - International journal of molecular …, 2019 - mdpi.com
Prostate cancer is the most prevalent non-skin cancer in men and is the leading cause of
cancer-related death. Early detection of prostate cancer is largely determined by a widely …

Interactions between cancer cells and bone microenvironment promote bone metastasis in prostate cancer

X Zhang - Cancer communications, 2019 - Springer
Bone metastasis is the leading cause of death in prostate cancer patients, for which there is
currently no effective treatment. Since the bone microenvironment plays an important role in …

UBC9 deficiency enhances immunostimulatory macrophage activation and subsequent antitumor T cell response in prostate cancer

J Xiao, F Sun, YN Wang, B Liu, P Zhou… - The Journal of …, 2023 - Am Soc Clin Investig
The role of tumor-associated macrophages (TAMs), along with the regulatory mechanisms
underlying distinct macrophage activation states, remains poorly understood in prostate …

Cancer metastasis: issues and challenges

CN Qian, Y Mei, J Zhang - Chinese journal of cancer, 2017 - Springer
Metastasis is the major cause of treatment failure in cancer patients and of cancer-related
deaths. This editorial discusses how cancer metastasis may be better perceived and …

Prognostic value of systemic immune‐inflammation index in patients with gastric cancer

K Wang, F Diao, Z Ye, X Zhang, E Zhai… - Cancer …, 2017 - Wiley Online Library
Background Inflammation‐based indexes have been used to predict survival and recurrence
in cancer patients. Systemic immune‐inflammation index (SII) was reported to be associated …

The multifaceted link between inflammation and human diseases

P Rajendran, YF Chen, YF Chen… - Journal of cellular …, 2018 - Wiley Online Library
Increasing reports on epidemiological, diagnostic, and clinical studies suggest that
dysfunction of the inflammatory reaction results in chronic illnesses such as cancer, arthritis …

Reprograming the tumor immunologic microenvironment using neoadjuvant chemotherapy in osteosarcoma

C Deng, Y Xu, J Fu, X Zhu, H Chen, H Xu… - Cancer …, 2020 - Wiley Online Library
Tumor‐infiltrating immune cells play a crucial role in tumor progression and response to
treatment. However, the limited studies on infiltrating immune cells have shown inconsistent …

Prognostic value of preoperative systemic immune-inflammation index in breast cancer: a propensity score-matching study

X Hua, ZQ Long, YL Zhang, W Wen, L Guo… - Frontiers in …, 2020 - frontiersin.org
Purpose: It was reported that the novel preoperative systemic immune-inflammation index
(SII) can predict survival in cases of many malignant tumors. However, the prognostic …

Prostate cancer immunotherapy—finally in from the cold?

KD Runcie, MC Dallos - Current oncology reports, 2021 - Springer
Abstract Purpose of Review Despite significant progress, patients with metastatic prostate
cancer continue to have poor prognosis. Immunotherapy has revolutionized cancer care for …

Chronic prostatitis/chronic pelvic pain syndrome and prostate cancer: study of immune cells and cytokines

Y Liu, R Mikrani, D Xie, J Wazir… - Fundamental & …, 2020 - Wiley Online Library
Prostate cancer and prostatitis are both significant health concerns. A large number of
studies have established that the occurrence of the two is closely related. However, the most …