Management of conjunctival malignant melanoma: a review and update

JR Wong, AA Nanji, A Galor, CL Karp - Expert review of …, 2014 - Taylor & Francis
Conjunctival malignant melanoma is a pigmented lesion of the ocular surface. It is an
uncommon but potentially devastating tumor that may invade the local tissues of the eye …

[HTML][HTML] Conjunctival melanoma: New insights in tumour genetics and immunology, leading to new therapeutic options

NJ Brouwer, RM Verdijk, S Heegaard… - Progress in Retinal and …, 2022 - Elsevier
Recent developments in oncology have led to a better molecular and cellular understanding
of cancer, and the introduction of novel therapies. Conjunctival melanoma (CoM) is a rare …

KIT Gene Mutations and Copy Number in Melanoma Subtypes

C Beadling, E Jacobson-Dunlop, FS Hodi, C Le… - Clinical Cancer …, 2008 - AACR
Purpose: We recently identified a KIT exon 11 mutation in an anorectal melanoma of a
patient who had an excellent response to treatment with imatinib. To determine the …

Conjunctival Melanomas Harbor BRAF and NRAS Mutations and Copy Number Changes Similar to Cutaneous and Mucosal Melanomas

KG Griewank, H Westekemper, R Murali, M Mach… - Clinical Cancer …, 2013 - AACR
Purpose: Conjunctival melanoma is a rare but potentially deadly tumor of the eye. Despite
effective local therapies, recurrence and metastasis remain frequent. Once the tumor has …

Advances in the management of conjunctival melanoma

GK Vora, H Demirci, B Marr, P Mruthyunjaya - Survey of ophthalmology, 2017 - Elsevier
Malignant melanoma of the conjunctiva is a rare but serious condition. Over the last several
years, there have been important advances in the classification, diagnosis, and treatment of …

BRAF mutations in conjunctival melanoma: investigation of incidence, clinicopathological features, prognosis and paired premalignant lesions

AC Larsen, C Dahl, CM Dahmcke… - Acta …, 2016 - Wiley Online Library
Purpose To investigate incidence, clinicopathological features and prognosis of BRAF‐
mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in …

NF1 mutations in conjunctival melanoma

SL Scholz, I Cosgarea, D Süßkind, R Murali… - British Journal of …, 2018 - nature.com
Background Conjunctival melanoma is a potentially deadly eye tumour. Despite effective
local therapies, tumour recurrence and metastasis remain frequent. The genetics of …

Malignant melanoma in the 21st century: the emerging molecular landscape

A Sekulic, P Haluska Jr, AJ Miller, JG De Lamo… - Mayo Clinic …, 2008 - Elsevier
Malignant melanoma presents a substantial clinical challenge. Current diagnostic methods
are limited in their ability to diagnose early disease and accurately predict individual risk of …

A retrospective review of conjunctival melanoma presentation, treatment, and outcome and an investigation of features associated with BRAF mutations

AC Larsen, CM Dahmcke, C Dahl… - JAMA …, 2015 - jamanetwork.com
Importance Large studies investigating clinical presentation and treatment in primary
conjunctival melanoma (CM) are rare. Clinicopathological characteristics ofBRAF-mutated …

TERT promoter mutations in ocular melanoma distinguish between conjunctival and uveal tumours

KG Griewank, R Murali, B Schilling, S Scholz… - British journal of …, 2013 - nature.com
Background: Recently, activating mutations in the TERT promoter were identified in
cutaneous melanoma. We tested a cohort of ocular melanoma samples for similar mutations …