Multiplexed imaging in oncology

C Andreou, R Weissleder, MF Kircher - Nature Biomedical Engineering, 2022 - nature.com
In oncology, technologies for clinical molecular imaging are used to diagnose patients,
establish the efficacy of treatments and monitor the recurrence of disease. Multiplexed …

Advanced nanotechnology leading the way to multimodal imaging‐guided precision surgical therapy

C Wang, W Fan, Z Zhang, Y Wen, L Xiong… - Advanced …, 2019 - Wiley Online Library
Surgical resection is the primary and most effective treatment for most patients with solid
tumors. However, patients suffer from postoperative recurrence and metastasis. In the past …

[HTML][HTML] Ultrabright gap-enhanced Raman tags for high-speed bioimaging

Y Zhang, Y Gu, J He, BD Thackray, J Ye - Nature communications, 2019 - nature.com
Surface-enhanced Raman spectroscopy (SERS) is advantageous over fluorescence for
bioimaging due to ultra-narrow linewidth of the fingerprint spectrum and weak photo …

[HTML][HTML] Non-invasive in vivo imaging of cancer using surface-enhanced spatially offset Raman spectroscopy (SESORS)

F Nicolson, B Andreiuk, C Andreou, HT Hsu… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: The goal of imaging tumors at depth with high sensitivity and specificity
represents a significant challenge in the field of biomedical optical imaging.'Surface …

[HTML][HTML] Design and synthesis of gold nanostars-based SERS nanotags for bioimaging applications

B Andreiuk, F Nicolson, LM Clark… - …, 2022 - ncbi.nlm.nih.gov
Surface-enhanced Raman spectroscopy (SERS) nanotags hold a unique place among
bioimaging contrast agents due to their fingerprint-like spectra, which provide one of the …

[HTML][HTML] DNA-enabled rational design of fluorescence-Raman bimodal nanoprobes for cancer imaging and therapy

S Pal, A Ray, C Andreou, Y Zhou, T Rakshit… - Nature …, 2019 - nature.com
Recently, surface-enhanced Raman scattering nanoprobes have shown tremendous
potential in oncological imaging owing to the high sensitivity and specificity of their …

Emergence of surface-enhanced Raman scattering probes in near-infrared windows for biosensing and bioimaging

H Chen, Z Cheng, X Zhou, R Wang, F Yu - Analytical Chemistry, 2021 - ACS Publications
The abnormal fluctuations of various biomarkers (such as intracellular nucleic acid, lipid,
protein, pH, etc.) can be used as valuable diagnostic indicators for monitoring the …

IR780-based nanomaterials for cancer imaging and therapy

L Wang, C Niu - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
IR780, a small molecule with a strong optical property and excellent photoconversion
efficiency following near infrared (NIR) irradiation, has attracted increasing attention in the …

Image‐guided tumor surgery: The emerging role of nanotechnology

NE Wojtynek, AM Mohs - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Surgical resection is a mainstay treatment for solid tumors. Yet, methods to distinguish
malignant from healthy tissue are primarily limited to tactile and visual cues as well as the …

MUC1 aptamer targeted SERS nanoprobes

S Pal, S Harmsen, A Oseledchyk… - Advanced functional …, 2017 - Wiley Online Library
Recently, surface‐enhanced Raman scattering (SERS) nanoprobes (NPs) have shown
promise in the field of cancer imaging due to their unparalleled signal specificity and high …