Region of interest (ROI) volumetric assessment has become a standard technique in
quantitative neuroimaging. ROI volume is thought to represent a coarse proxy for making …

The habenula (Hb) is an evolutionary well-conserved structure located in the epithalamus.
The Hb receives inputs from the septum, basal ganglia, hypothalamus, anterior cingulate …

Light plays a pivotal role in the regulation of affective behaviors. However, the precise
circuits that mediate the impact of light on depressive-like behaviors are not well understood …

The underlying mechanisms of bright light therapy (BLT) in the prevention of individuals with
subthreshold depression symptoms are yet to be elucidated. The goal of the study was to …

Expertise and training in fine motor skills has been associated with changes in brain
structure, function, and connectivity. Fewer studies have explored the neural effects of …

Background Ketamine's potent and rapid antidepressant properties have shown great
promise to treat severe forms of major depressive disorder (MDD). A recently hypothesized …

Objective To characterize the functional connectivity (FC) of target brain regions for deep
brain stimulation (DBS) in patients with treatment-resistant depression (TRD), and to …

The habenula has been implicated in the pathogenesis of pain and analgesia, while
evidence concerning its function in chronic low back pain (cLBP) is sparse. This study aims …

The habenula is a small midbrain structure that is important for brain signaling and learning
from negative events. Thus, the habenula is strongly connected to both the reward system …

Background The diagnosis of subclinical depression (SD) currently relies exclusively on
subjective clinical scores and structured interviews, which shares great similarities with …