Therapeutic use of mesenchymal stromal cells: the need for inclusive characterization guidelines to accommodate all tissue sources and species

A Wright, ML Arthaud-Day, ML Weiss - Frontiers in cell and …, 2021 - frontiersin.org
Following their discovery over 50 years ago, mesenchymal stromal cells (MSCs) have
become one of the most studied cellular therapeutic products by both academia and industry …

Immunomodulatory effect of adipose-derived stem cells: the cutting edge of clinical application

S Ceccarelli, P Pontecorvi, E Anastasiadou… - Frontiers in cell and …, 2020 - frontiersin.org
Adipose-derived stem cells (ASCs) represent a promising tool for soft tissue engineering as
well as for clinical treatment of inflammatory and autoimmune pathologies. The well …

A review of fetal bovine serum in the culture of mesenchymal stromal cells and potential alternatives for veterinary medicine

CR Pilgrim, KA McCahill, JG Rops… - Frontiers in Veterinary …, 2022 - frontiersin.org
Fetal bovine serum (FBS) remains widely used as a supplement in cell culture media used
in the isolation and expansion of mesenchymal stromal cells (MSC) despite longstanding …

Stem cells for treatment of liver fibrosis/cirrhosis: clinical progress and therapeutic potential

P Liu, Y Mao, Y Xie, J Wei, J Yao - Stem Cell Research & Therapy, 2022 - Springer
Cost-effective treatment strategies for liver fibrosis or cirrhosis are limited. Many clinical trials
of stem cells for liver disease shown that stem cells might be a potential therapeutic …

Stem cells in veterinary medicine—current state and treatment options

M Voga, N Adamic, M Vengust… - Frontiers in veterinary …, 2020 - frontiersin.org
Regenerative medicine is a branch of medicine that develops methods to grow, repair, or
replace damaged or diseased cells, organs or tissues. It has gained significant momentum …

Immunosuppressive effects of mesenchymal stem cells-derived exosomes

X Qian, N An, Y Ren, C Yang, X Zhang, L Li - Stem cell reviews and reports, 2021 - Springer
Mesenchymal stem cells (MSCs) have become important seed cells in therapy because of
their immunosuppressive function and anti-inflammatory effects. MSCs exert …

Mesenchymal stem cells in suppression or progression of hematologic malignancy: current status and challenges

MW Lee, S Ryu, DS Kim, JW Lee, KW Sung, HH Koo… - Leukemia, 2019 - nature.com
Mesenchymal stem cells (MSCs) are known for being multi-potent. However, they also
possess anticancer properties, which has prompted efforts to adapt MSCs for anticancer …

Canine mesenchymal stem cells from synovium have a higher chondrogenic potential than those from infrapatellar fat pad, adipose tissue, and bone marrow

A Sasaki, M Mizuno, N Ozeki, H Katano, K Otabe… - PLoS …, 2018 - journals.plos.org
Osteoarthritis (OA), a common chronic joint disorder in both humans and canines, is
characterized by a progressive loss of articular cartilage. Canines can serve as an animal …

[HTML][HTML] Comparative analysis and characterization of soluble factors and exosomes from cultured adipose tissue and bone marrow mesenchymal stem cells in canine …

AJ Villatoro, C Alcoholado, MC Martín-Astorga… - Veterinary immunology …, 2019 - Elsevier
The two main sources of mesenchymal stem cell (MSCs) in the canine species are bone
marrow (cBM-MSCs) and adipose tissue (cAd-MSCs). The secretion of multitude bioactive …

Adipose tissue-derived mesenchymal stromal/stem cells, obesity and the tumor microenvironment of breast cancer

A Ritter, NN Kreis, SC Hoock, C Solbach, F Louwen… - Cancers, 2022 - mdpi.com
Simple Summary Adipose tissue is the major microenvironment of breast cancer. Adipose
tissue-derived mesenchymal stromal/stem cells (ASCs/MSCs) are key players in adipose …