Tendon is a highly specialized, hierarchical tissue designed to transfer forces from muscle to
bone; complex viscoelastic and anisotropic behaviors have been extensively characterized …

The repair of subcutaneous tendon ruptures can be stimulated by a single application of one
of several growth factors [eg platelet-derived growth factor (PDGF), transforming growth …

How mechanical stress affects physical performance via tendons is not fully understood.
Piezo1 is a mechanosensitive ion channel, and E756del PIEZO1 was recently found as a …

Allogenic fibrin glue was originally described in 1970, and is formed by polymerising
fibrinogen with thrombin and calcium. 18 The first reference in the scientific literature to the …

Muscle forces are essential for skeletal patterning during development. Eliminating muscle
forces, eg, through paralysis, leads to bone and joint deformities. Botulinum toxin (BtxA) …

Injured tendons require mechanical tension for optimal healing, but it is unclear which genes
are upregulated and responsible for this effect. We unloaded one Achilles tendon in rats by …

Ultrasound elastography is an emerging set of imaging modalities used to image tissue
elasticity and are often referred to as virtual palpation. These techniques have proven …

The mechanical response of a tendon to load is strictly related to its complex and highly
organized hierarchical structure, which ranges from the nano-to macroscale. In a broader …

Dynamic loading is a shared feature of tendon tissue homeostasis and pathology. Tendon
cells have the inherent ability to sense mechanical loads that initiate molecular-level …

It has been postulated that human tendons are viscoelastic and their mechanical properties
time-dependent. Although Achilles tendon (AT) mechanics are widely reported, there is no …