Fibrosis is defined as an excessive deposition of connective tissue components and can
affect virtually every organ system, including the skin, lungs, liver and kidney. Fibrotic tissue …

Transforming growth factor-β (TGF-β) is widely recognized as a core pathway of fibrosis.
Inhibition of TGF-β signaling may thus offer potential for antifibrotic therapies. Long-term …

Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of hepatic
histopathological changes ranging from non-inflammatory intracellular fat deposition to non …

MicroRNAs (miRNAs) are a class of short non-coding RNA molecules that have attracted
tremendous attention from the biological and biomedical research communities over the …

Nutrients can reverse or change epigenetic phenomena such as DNA methylation and
histone modifications, thereby modifying the expression of critical genes associated with …

MicroRNAs miR-122, miR-34a, miR-16 and miR-21 are commonly deregulated in liver
fibrosis and hepatocellular carcinoma. This study examined whether circulating levels of …

Abstract MicroRNA-34a (miR-34a) is thought to be involved in nonalcoholic fatty liver
disease (NAFLD). However, the association between altered expression of miR-34a and the …

Background In many industrialized countries, non-alcoholic fatty liver disease (NAFLD) is
recognized as an important disease that increases the risk of cardiovascular disease, type-2 …

Simple Summary Hepatocellular carcinoma (HCC) is an aggressive human cancer and is
caused as consequences of chronic liver diseases. Although HCC is more common in …

BACKGROUND & AIMS: Non-alcoholic fatty liver disease (NAFLD) comprises a spectrum of
stages from simple steatosis to non-alcoholic steatohepatitis (NASH). However, disease …