Microtubule-interfering drugs: current and future roles in epithelial ovarian cancer treatment

J Tymon-Rosario, NN Adjei, DM Roque, AD Santin - Cancers, 2021 - mdpi.com
Simple Summary Microtubule-interfering drugs have been used alone or in combination in
the treatment of epithelial ovarian cancer. Over the years and with increasing …

[HTML][HTML] Development of novel derivatives of stilbene and macrocyclic compounds as potent of anti-microtubule factors

F Borys, P Tobiasz, M Poterała, H Krawczyk - Biomedicine & …, 2021 - Elsevier
Microtubules (composed of α-and β-tubulin heterodimers) ubiquitous cellular polymers are
important components of the cytoskeleton and play diverse roles within the cell, such as …

Modulating protein–protein interactions by cyclic and macrocyclic peptides. Prominent strategies and examples

R González-Muñiz, MÁ Bonache, MJ Pérez de Vega - Molecules, 2021 - mdpi.com
Cyclic and macrocyclic peptides constitute advanced molecules for modulating protein–
protein interactions (PPIs). Although still peptide derivatives, they are metabolically more …