Traumatic brain injury (TBI) and Alzheimer's disease (AD) represent 2 of the largest sources
of death and disability in the United States. Recent studies have identified TBI as a potential …

The inflammasome is a multimeric protein complex located in the cytoplasm that is activated
by many factors and subsequently promotes the release of proinflammatory factors such as …

Abstract Background According to the Chinese Pharmacopoeia, the fruit of Schisandra
chinensis (Turcz.) Baill.(SC) is an important traditional Chinese medicine that can be used to …

Mammalian (or mechanistic) target of rapamycin complex 2 (mTORC2) is a kinase complex
that targets predominantly Akt family proteins, SGK1 and protein kinase C (PKC), and has …

Background Liver fibrosis is a reversible wound-healing response that can lead to end-stage
liver diseases without effective treatment, in which HBV infection is a major cause. However …

Ménière's disease, a multifactorial disorder of the inner ear, is characterized by severe
vertigo episodes and hearing loss. Although the role of immune responses in Ménière's …

中性粒细胞胞外诱捕网(neutrophilextracellulartraps, NETs) 是由组蛋白和中性粒细胞颗粒蛋白
组成的DNA 网状结构, 在中性粒细胞捕获和杀死病原体过程中起重要作用. 在心肌梗死过程中 …

It is widely accepted that inflammation is an important risk for the development of prostate
cancer (PCa). The objective of this study was designed to investigate the potential molecular …

Cl− movement and Cl−-sensitive signal pathways contributes to the survival and switch of
inflammatory phenotype of microglia and are believed to play a key role in the inflammatory …

Stroke has emerged as the primary cause of disability and death globally in recent years.
Intracerebral hemorrhage (ICH), a particularly severe kind of stroke, is occurring in an …