Alpha-ketoglutarate (AKG) is a key molecule in the Krebs cycle determining the overall rate
of the citric acid cycle of the organism. It is a nitrogen scavenger and a source of glutamate …

Abstract l-Glutamine is a nutritionally semi-essential amino acid for proper growth in most
cells and tissues, and plays an important role in the determination and guarding of the …

Glutamate is a main constituent of dietary protein and is also consumed in many prepared
foods as an additive in the form of monosodium glutamate. Evidence from human and …

An intermediate of tricarboxylic acid cycle alpha-ketoglutarate (AKG) is involved in
pleiotropic metabolic and regulatory pathways in the cell, including energy production …

Abstract α-Ketoglutarate (AKG) is a key intermediate in glutamine metabolism. Emerging
evidence shows beneficial effects of AKG on clinical and experimental nutrition, particularly …

Neonates are at increased risk for inflammatory bowel disease, but effective prevention and
treatments are currently limited. This study was conducted with the lipopolysaccharide (LPS) …

This study was conducted using the piglet model to test the hypothesis that mucosal cells of
the neonatal small intestine can degrade nutritionally essential amino acids (EAA) …

Endogenous protein leaving the ileum largely consists of accrued mucins from the upper
gastrointestinal tract (GIT) that had resisted digestion. The amounts released rely on their …

There is growing interest in glutamate as a functional amino acid in nutrition and health. This
study was conducted to determine whether glutamate precursor α-ketoglutarate (AKG) could …

The present study determined whether α-ketoglutarate (AKG) might affect the expression of
AMP-activated protein kinase (AMPK) and energy status in the intestinal mucosa of piglets …