Actinobacteriophages are viruses that infect bacterial hosts in the phylum Actinobacteria.
More than 17,000 actinobacteriophages have been described and over 3,000 complete …

Mycobacteriophages—bacteriophages infecting Mycobacterium hosts—contribute
substantially to our understanding of viral diversity and evolution, provide resources for …

The development of new drug regimens that allow rapid, sterilizing treatment of tuberculosis
has been limited by the complexity and time required for genetic manipulations in …

The past three years have seen an escalation in the number of sequenced bacteriophage
genomes with more than 500 now in the NCBI phage database, representing a more than …

Mycobacteriophages are viruses that infect mycobacterial hosts. Expansion of a collection of
sequenced phage genomes to a total of 60—all infecting a common bacterial host …

The 'Appelmans protocol'is used by Eastern European researchers to generate therapeutic
phages with novel lytic host ranges. Phage cocktails are iteratively grown on a suite of …

Advances in DNA sequencing technology have facilitated the determination of hundreds of
complete genome sequences both for bacteria and their bacteriophages. Some of these …

Bacteriophages (phages) evolve rapidly by acquiring genes from other phages. This results
in mosaic genomes. Here, we identify numerous genetic transfers between distantly related …

Two efficient recombination systems were combined to produce a versatile method for
chromosomal engineering that obviates the need to prepare double-stranded DNA (dsDNA) …

Mycobacteriophages are viruses that infect mycobacterial hosts. A large number of
mycobacteriophages have been isolated and genomically characterized, providing insights …