In liver and intestine, transporters play a critical role in maintaining the enterohepatic
circulation and bile acid homeostasis. Over the past two decades, there has been significant …

Dietary fiber is plant-derived material that is resistant to digestion by human alimentary
enzymes. Fiber may be divided into two broad chemical classes: 1) non-alpha-glucan …

Bridging the gap between basic scientific advances and the understanding of liver disease—
the extensively revised new edition of the premier text in the field. The latest edition of The …

Balance studies, which focused on bile acid metabolism, were carried out on 9 patients with
ileal resection in order to define the importance of bile acid malabsorption in the …

Supersaturation of bile with cholesterol predisposes to the development of cholesterol
gallstones. To identify the factors determining cholesterol saturation of bile, we analyzed the …

Lithocholic acid, a monohydroxy, secondary bile acid, is formed by bacterial 7‐
dehydroxylation of the primary bile acid chenodeoxycholic acid (CDCA) and of the …

Membrane transporters expressed by the hepatocyte and enterocyte play critical roles in
maintaining the enterohepatic circulation of bile acids, an effective recycling and …

Both basic and clinical aspects are stressed, including the biochemical, anatomic,
physiologic, and pathologic. Emphasis is on the diagnosis and treatment of liver disease …

Cholesterol gallstone disease is initiated in a liver which produces abnormal bile with
excess cholesterol relative to bile salts and phospholipid. To define the responsible …

The mechanisms for the hypolipidemic action of nicotinic acid were examined in 12 patients
with hyperlipidemia. Most patients were studied in the hospital on a metabolic ward. The first …