Brain malignancies encompass a range of primary and metastatic cancers, including low-
grade and high-grade gliomas and brain metastases (BrMs) originating from diverse …

The endoplasmic reticulum quality control (ERQC) system, including endoplasmic reticulum-
associated degradation (ERAD), the unfolded protein response (UPR), and autophagy …

High-dose dexamethasone (DEX) is used to treat chemotherapy-induced nausea and
vomiting or to control immunotherapy-related autoimmune diseases in clinical practice …

To survive, mammalian cells must adapt to environmental challenges. While the cellular
response to mild stress has been widely studied, how cells respond to severe stress remains …

Neovascular age‐related macular degeneration (AMD), which is characterized by choroidal
neovascularization (CNV), leads to vision loss. M2 macrophages produce vascular …

Introduction The current approaches that are used to treat ischemic stroke suffer from poor
targeting, lack of effectiveness, and potential off-target effects, necessitating the …

Background Phenotypic switching of vascular smooth muscle cells (VSMCs) plays a key role
in atherosclerosis. We aimed to investigate whether Homocysteine-responsive endoplasmic …

The emergence of drug-resistant Mycobacterium tuberculosis (M. tb) has led to the
development of novel anti-tuberculosis (anti-TB) drugs. Common methods for testing the …

Given the rapid development in the field of nanotechnology, the potential toxicity of carbon
nanotubes (CNTs) in humans has received much attention in recent years. However, the …

The ingestion of excessive free fatty acid could induce lipotoxicity in tissues and then lead to
the initiation of many metabolism diseases. In this work, the protective effect of apigenin on …