Adverse stressful experiences in utero can redirect fetal brain development, ultimately
leading to increased risk for psychiatric disorders. Obesity during pregnancy can have …

Neurodegenerative disorders are accompanied by neuronal degeneration and glial
dysfunction, resulting in cognitive, psychomotor, and behavioral impairment. Multiple factors …

Several lines of evidence suggest that the dysregulation of the immune system is an
important factor in the development of depression. Microglia are the resident macrophages …

Abstract Purpose of Review Dietary obesity is primarily attributed to an imbalance between
food intake and energy expenditure. Adherence to lifestyle interventions reducing weight is …

Pain, one of the most important problems in the field of medicine and public health, has
great research significance. Opioids are still the main drugs to relieve pain now. However, its …

Rheumatoid arthritis (RA) is an inflammatory joint disease with a neurological component
including depression, cognitive deficits, and pain, which substantially affect patients' quality …

Multiple lines of evidence support the pathogenic role of maternal immune activation (MIA)
in the occurrence of the schizophrenia-like disturbances in offspring. While in the brain the …

Early life challenges resulting from maternal immune activation (MIA) may exert persistent
effects on the offspring, including the development of psychiatric disorders, such as …

Depression and cognitive dysfunction share a common neuropathological platform.
Abnormal neural plasticity in the frontolimbic circuits has been linked to changes in the …

Currently, much attention is focused on the influence of mitochondrial disturbances at the
onset of depression. The goal of this study was to investigate the impact of prenatal stress …